Results 51 to 60 of about 414,139 (307)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Review of grid integration and operation technologies for large-scale offshore wind power

电力工程技术
In the context of China's strategic goals of achieving carbon peak and carbon neutrality, as well as the construction of a new power system and a new energy system, offshore wind power has become an important direction for the development of renewable ...
Jizhong ZHU, Meiyun GAO, Pengfei XIAO, Hanjiang DONG, Haohao ZHU, Kaixin LIN   +5 more
doaj   +1 more source

Stochastic Sizing of Energy Storage Systems for Wind Integration [PDF]

Engineering, Technology & Applied Science Research, 2018
In this paper, we present an optimal capacity decision model for energy storage systems (ESSs) in combined operation with wind energy in power systems. We use a two-stage stochastic programming approach to take into account both wind and load uncertainties. The planning problem is formulated as an AC optimal power flow (OPF) model with the objective of
Duong D. Le, Nhi T. A. Nguyen
openaire   +1 more source

Load-shedding probabilities with hybrid renewable power generation and energy storage [PDF]

, 2010
The integration of renewable energy resources, such as solar and wind power, into the electric grid presents challengs partly due to the intermittency in the power output. These difficulties can be alleviated by effectively utilizing energy storage.
Chandy, K. Mani, Clarke, Christopher R., Low, Steven H., Topcu, Ufuk, Xu, Huan   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Energy storage for wind integration: Hydropower and other contributions [PDF]

2012 IEEE Power and Energy Society General Meeting, 2012
The amount of wind power and other timevariable non-dispatchable renewable energy sources (RES) is rapidly increasing in the world. A few power systems are already facing very high penetrations from variable renewables which can surpass the systems' consumption during no-load periods, requiring the energy excess to be curtailed, exported or stored. The
Estanqueiro, A., Ardal, A.R., O'Dwyer, C., Flynn, D., Huertas-Hernando, D., Lew, D., Gomez-Lazaro, E., Ela, E., Revuelta, J., Kiviluoma, Juha, Rodrigues, L., Amelin, M., Holttinen, Hannele   +13 more
openaire   +3 more sources

Evaluation of the integration of the Wind-Induced Flutter Energy Harvester (WIFEH) into the built environment: experimental and numerical analysis [PDF]

, 2017
With the ubiquity of low-powered technologies and devices in the urban environment operating in every area of human activity, the development and integration of a low-energy harvester suitable for smart cities applications is indispensable. The multitude
Aquino, Angelo I., Calautit, John Kaiser, Hughes, Ben Richard   +2 more
core   +4 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Wind energy penetration impact on active power flow in developing grids

Scientific African, 2022
Renewable energy (RE) generators are typically connected to the grid via the distribution network or transmission network load buses. With today’s large-capacity RE generators, such as wind turbines, and the environmental concerns, these RE generators ...
Innocent O. Ozioko, Nnaemeka S. Ugwuanyi, Arthur O. Ekwue, Charles I. Odeh   +3 more
doaj   +1 more source