Results 151 to 160 of about 102,683 (311)

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

A comparison between computational fluid dynamics (CFD) analysis and wind tunnel observations on flow above a complex terrain

open access: yes, 2006
A combined RANS/LES hybrid strategy was developed for flow field simulation to gauge the accuracy against wind tunnel observations. Flow across a hilly terrain was predicted by solving the RANS equations with the k-ε turbulence model of the whole field ...
Kwok, Kenny C. S.   +3 more
core  

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Numerical and Experimental Investigation of Thickness Effect on the Cambered Airfoils at Low Reynolds Numbers

open access: yesHavacılık ve Uzay Teknolojileri Dergisi
In this study, experimentaland numerical study for the cambered airfoils was conducted at Re = 1.5x105and Re = 2.5x105and different angles of attack.
Muhammer Ayvazoğlu   +7 more
doaj  

Testing of the FolksWind 1.5kW vertical axis wind turbine

open access: yes, 2011
In recent years the small wind industry has shown exponential growth; however there have been growing concerns over the safety and reliability of small wind turbines on the market. The International Electrotechnical Committee and the International Energy
Williamson, Bethany
core  

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