Results 61 to 70 of about 790,941 (303)
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Validation of Danish wind time series from a new global renewable energy atlas for energy system analysis [PDF]
We present a new high-resolution global renewable energy atlas ({REatlas}) that can be used to calculate customised hourly time series of wind and solar PV power generation.
Andresen, Gorm Bruun +2 more
core +1 more source
Radiative Transfer and Generalized Wind
Dissimilar flows can be compared by exploiting the fact that all flux densities divided by their conjugate volume densities form velocity fields, which have been described as generalized winds. These winds are an extension of the classical notion of wind in fluids which puts these distinct processes on a common footing, leading to thermodynamical ...
Christopher Essex, Indrani Das
openaire +3 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Dynamic Frequency Support from a DFIG-Based Wind Turbine Generator via Virtual Inertia Control
As the penetrated level of wind in power grids increases, the online system inertia becomes weak. Doubly-fed induction generator (DFIG)-based wind turbine generators (WTGs) are required to provide virtual inertia response to support system frequency. The
Dejian Yang +3 more
doaj +1 more source
Uncertainty Sets for Wind Power Generation [PDF]
As penetration of wind power generation increases, system operators must account for its stochastic nature in a reliable and cost-efficient manner. These conflicting objectives can be traded-off by accounting for the variability and uncertainty of wind power generation.
Dvorkin, Yury +3 more
openaire +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The degradation of electrical insulation is mainly attributed to local defects. Although incorporating organic small molecules into dielectric polymers promotes the insulation strength, accurate suppression of defect development is a long-term and ...
Ke Li +6 more
doaj +1 more source

