Results 171 to 180 of about 202,211 (313)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Optimising hybrid renewable energy systems for remote tribal villages: A techno-economic case study from central and Eastern India. [PDF]

Sci Rep
Sekhar YR, Chiranjeevi C, Ravindra, Asif M, Hamida MBB, Syum GG.   +5 more
europepmc   +1 more source

Summary of NASA Lewis Research Center solar heating and cooling and wind energy programs [PDF]

Plans for the construction and operation of a solar heating and cooling system in conjunction with a office building being constructed at Langley Research Center, are discussed.
Vernon, R. W.
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Fuzzy-logic-controlled DVR for enhancing the fault resilience of wind energy conversion systems. [PDF]

Sci Rep
Nori AM, Abdulabbas AK, Al Garni HZ, Mbasso WF, Alruwaili M, ELrashidi A.   +5 more
europepmc   +1 more source

Broad band sound from wind turbine generators [PDF]

Brief descriptions are given of the various types of large wind turbines and their sound characteristics. Candidate sources of broadband sound are identified and are rank ordered for a large upwind configuration wind turbine generator for which data are ...
Grosveld, F. W., Hubbard, H. H., Shepherd, K. P.   +2 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Adaptive reinforcement learning framework for sustainable microgrid optimization in arid urban environments. [PDF]

Sci Rep
Mohamed MAS, Almazam K, Alzahrani M, Majrashi AA, Garo OO, Lagebo ML.   +5 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Enhanced power capture for the wind turbine system via a novel second-order nonsingular fast terminal sliding mode control strategy. [PDF]

Sci Rep
Shalbafian A, Amiri F.
europepmc   +1 more source