Results 71 to 80 of about 25,038 (263)

Evaluation of a Database of the Spanish Wind Energy Resources Derived from a Regional Reanalysis

open access: yesEnergies
An enhanced database (RetroDB) of the Spanish wind energy resources, derived from a high spatial resolution integration with the WRF model, is proposed and evaluated.
Antonio Jiménez-Garrote   +5 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Optimization Scheduling of Multi-Regional Systems Considering Secondary Frequency Drop

open access: yesEnergies
After primary frequency regulation in large-scale wind farms is completed, the power dip phenomenon occurs during the rotor speed recovery phase. This phenomenon may induce a secondary frequency drop in power systems, which poses challenges to system ...
Xiaodong Yang   +4 more
doaj   +1 more source

Dynamic Analysis of Wind Turbine Gearbox Components

open access: yesEnergies, 2016
This paper studies the dynamic response of a wind turbine gearbox under different excitation conditions. The proposed 4 degree-of-freedom (DOF) dynamic model takes into account the key factors such as the time-varying mesh stiffness, bearing stiffness ...
Mingming Zhao, Jinchen Ji
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Optimization Scheduling Strategy for Coal Railway Integrated Energy Systems

open access: yesEnergies
This paper proposes an optimal scheduling strategy for coal-dedicated railway integrated energy systems, leveraging coordinated electric boiler and thermal storage operation to enhance economic efficiency, improve wind power integration, and reduce ...
Xiangdong Lou   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Energy storage-based control of multi-terminal DC grid to eliminate the fluctuations of renewable energy

open access: yesThe Journal of Engineering, 2019
DC grid technology is an effective approach to implement large-scale renewable energy integration and accommodation. However, because of randomness and volatility of renewable power generation, the stability and efficiency of the power grid with high ...
Jiajun Nan, Wei Yao, Jinyu Wen
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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