Results 41 to 50 of about 3,828,803 (394)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Augmented Kalman filter with a reduced mechanical model to estimate tower loads on a land-based wind turbine: a step towards digital-twin simulations

Wind Energy Science, 2020
. This article presents an application of the Kalman filtering technique to estimate loads on a wind turbine. The approach combines a mechanical model and a set of measurements to estimate signals that are not available in the measurements, such as wind ...
E. Branlard, Dylan Giardina, Cameron Brown   +2 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

From Strain to Loads: Development of a Measurement Solution for Wind Turbine Transmission Input Loads during Drivetrain Testing

Sensors, 2023
As wind energy is paving the way for the energy transition from fossil to renewable energy sources, the ongoing trend of increasing the rated power of wind turbines aims to reduce the overall cost of wind energy.
Eren Bilen, Baher Azzam, Ralf Schelenz, Tim Runkel, Malte Raddatz, Georg Jacobs   +5 more
doaj   +1 more source

Wind tunnel model damper [PDF]

, 1971
Damper system for alleviating air flow shock loads on wind tunnel ...
Bryan, M. B.
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Coupling Vibration Characteristics and Wind-Induced Responses of Large-Span Transmission Lines Under Multi-Dimensional Wind

Buildings
Transmission lines, crucial for power and urban infrastructure, are vulnerable to wind damage; this paper addresses research gaps in tower-line systems under multi-dimensional wind loads and aerodynamic damping.
Wenping Xie, Zhenhua Li, Wenlong Du, Xing Fu   +3 more
doaj   +1 more source

Wind-induced tower crane vibration and safety evaluation

Journal of Low Frequency Noise, Vibration and Active Control, 2020
The maximum wind load direction of tower crane is considered to be perpendicular to its jib. The interference effects of its different segments and across-wind loads are ignored in traditional crane safety evaluation. This study proposes a general scheme
Wei Chen, Xianrong Qin, Zhigang Yang, Pengming Zhan   +3 more
doaj   +1 more source

Nonlinear Destructive Interaction between Wind and Wave Loads Acting on the Substructure of the Offshore Wind Energy Converter: A Numerical Study

Journal of Marine Science and Engineering, 2020
Even though the offshore wind industry’s growth potential is immense, the offshore wind industry is still suffering from problems, such as the large initial capital requirements. Many factors are involved, and among these, the extra costs incurred by the
Yong Jun Cho
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source