Results 31 to 40 of about 83,912 (251)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Power Flow Optimizaiton Control in AC / DC Hybrid Distribution Network Based on Power Router

open access: yesJournal of Harbin University of Science and Technology, 2021
In recent years,a large number of distributed new energy power generation devices have been integrated into the grid,resulting in bidirectional power flow in distribution network.
YIN Zhan   +6 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Experimental Analysis on Friction Characteristics of MW Wind Turbine Generator Yaw Braking System

open access: yes南方能源建设
[Objective] The wind turbine generator (WTG) yaw braking system has application in low-pressure yaw and high-pressure heavy load, and the friction performance between friction pairs is influenced by various parameters between the components of the yaw ...
Ming LIU   +4 more
doaj   +1 more source

A New Technology Research for Scour Protection of Offshore Wind Turbine Foundation

open access: yes南方能源建设, 2020
[Introduction] With the rapid development of offshore wind power in China, large diameter monopile foundation is be widely used. At the same time, the scour of foundation is becoming more and more serious.
HE Qingdong, QI Jiangong
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Design and Verification of Large-Diameter Tower Sharding Platform for Wind Turbine

open access: yes南方能源建设
[Objective] In recent years, the wind turbine diameter of wind turbine has become larger and larger, which makes the wind load borne by the tower barrel more and more.
Jiawen LAN   +3 more
doaj   +1 more source

Grid-Connected Adaptive Analysis and Control of the DC Wind Turbine Under the Grid-Side Transient Faults

open access: yesIEEE Access, 2023
The grid-side transient fault ride-through problem seriously affects the stable operation of the grid-connected wind turbine. At present, the grid-connected adaptability analysis of DC wind turbine (DCWT) under the grid-side transient faults is still a ...
Zhanlong Li   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Evaluation of Wear Models for the Wear Calculation of Journal Bearings for Planetary Gears in Wind Turbines

open access: yesLubricants, 2023
To increase the power density of the electromechanical drive train of wind turbines, journal bearings can be used as planetary gear bearings instead of rolling bearings. This technological change presents new challenges.
Benjamin Lehmann   +3 more
doaj   +1 more source

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