Results 61 to 70 of about 519,891 (291)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Offshore Wind Power Plant Technology Catalogue - Components of wind power plants, AC collection systems and HVDC systems [PDF]

open access: yes, 2017
Traditionally, Offshore Wind Power Plants (OWPPs) are connected through many com-ponents as shown in the figure 1. An OWPP consists of controllable, variable speed Wind Turbines (WTs). These WTs are connected through Medium Voltage (MV) sub-marine cables typically at voltage level of upto 33-66 kV to the Offshore Alterna-ting Current (AC) substation ...
Das, Kaushik   +1 more
openaire  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

In-Network Distributed Solar Current Prediction [PDF]

open access: yes, 2014
Long-term sensor network deployments demand careful power management. While managing power requires understanding the amount of energy harvestable from the local environment, current solar prediction methods rely only on recent local history, which makes
Basha, Elizabeth   +2 more
core   +2 more sources

Reactive power-voltage hybrid model predictive control method for wind-storage power stations

open access: yesInternational Journal of Sustainable Energy
This paper proposes a hybrid model predictive control strategy for wind farms with energy storage. Building on traditional predictive control, it integrates a neural network-based wind power forecasting model and an energy storage system.
Shulong Zhang   +6 more
doaj   +1 more source

Field‐data‐based reliability analysis of power converters in wind turbines: Assessing the effect of explanatory variables

open access: yesWind Energy, 2023
Frequent failures of power converters affect the availability of wind turbines and cause considerable maintenance costs. To enhance the reliability of power converters in wind turbines, the prevailing causes and modes of failures have to be identified ...
Karoline Pelka, Katharina Fischer
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Control and monitoring of solar photovoltaic panel using PLC [PDF]

open access: yes, 2013
A renewable energy source plays an important role in electricity generation. Various renewable energy sources like wind, solar, geothermal, ocean thermal, and biomass can be used for generation of electricity and for meeting our daily energy needs ...
Mohd Jamil, Johanis
core  

Risk-Averse Model Predictive Operation Control of Islanded Microgrids

open access: yes, 2019
In this paper we present a risk-averse model predictive control (MPC) scheme for the operation of islanded microgrids with very high share of renewable energy sources.
Hans, Christian A.   +4 more
core   +1 more source

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