Results 61 to 70 of about 32,380 (261)
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
The Weibull probability density function (PDF) has mostly been used to fit wind speed distributions for wind energy applications. The goodness of fit of the results depends on the estimation method that was used and the wind type of the analyzed area. In
Camilo Carrillo +3 more
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
The assessment of wind energy potential is essential for sustainable energy planning, particularly in Africa, where renewable energy sources are increasingly considered for power generation.
Francis Olatunbosun Aweda +7 more
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Evaluation of wind energy potential in the south-south geopolitical zone of Nigeria
This study examined wind energy potential of six selected locations the South-South geopolitical zone of Nigeria using 10 year wind data obtained at a height of 10m as a possible location for energy generation from wind.
B Eboibi, O Eboibi, E Okubio, C Iyasele
doaj +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Characterisation of wind speed series and power in Durban
Both the planning and operating of a wind farm demand an appropriate wind speed model of its location. The model also helps predict the dynamic behaviour of wind turbines and wind power potential in the location.
Ayele Nigussie Legesse +2 more
doaj +1 more source
Security Constrained Unit Commitment with Extreme Wind Scenarios
The rapid development of economy and society stimulates the increase of power demand. Wind power has received great attention as a typical renewable energy, and the share of wind power is continually increasing in recent years.
Xin Zhu, Zongchao Yu, Xuan Liu
doaj +1 more source

