Results 41 to 50 of about 18,839 (266)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Impedance Analysis and PHIL Demonstration of Reactive Power Oscillations in a Wind Power Plant Using a 4-MW Wind Turbine

open access: yesFrontiers in Energy Research, 2020
This paper presents impedance-based analysis, mitigation, and power-hardware-in-the-loop (PHIL) demonstration of reactive power oscillations in a wind power plant using a 4-MW Type III wind turbine drivetrain.
Przemyslaw Koralewicz   +7 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Censuses and Observations from a Raptor Migration Bottleneck, Hatay Turkey: Phenology and Threats

open access: yesПернатые хищники и их охрана, 2018
Hatay is one of the most important bottlenecks for soaring bird migration in the Palearctic region. It is the meeting point of two different migration routes from Europe and Asia. Unfortunately, bird migration monitoring studies have not been extensively 
İlker Özbahar, Mehmet Gül
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Lowering post‐construction yield assessment uncertainty through better wind plant power curves

open access: yesWind Energy, 2022
Many operational analyses of wind power plants require a statistical relationship, which can be called the wind plant power curve, to be developed between wind plant energy production and concurrent atmospheric variables.
Nicola Bodini   +4 more
doaj   +1 more source

Influence of Environmental Factors on the Intelligent Management of Photovoltaic and Wind Sections in a Hybrid Power Plant

open access: yesEnergies, 2023
The high-efficiency operation of photovoltaic and wind systems is affected by many factors and parameters that should be continuously monitored.
Jacek Kusznier
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

White‐tailed eagles (Haliaeetus albicilla) at the Smøla wind‐power plant, Central Norway, lack behavioral flight responses to wind turbines

open access: yesWildlife Society Bulletin, 2013
Evidence is increasing of bird mortality due to large‐scale wind‐energy development. Soaring raptors, such as the white‐tailed eagle (Haliaeetus albicilla), have proven particularly vulnerable to collisions.
Espen Lie Dahl   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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