Results 101 to 110 of about 759,108 (306)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

WIND TURBULENCE OVER SEAS IN TROPICAL CYCLONES

open access: yesCoastal Engineering Proceedings, 1982
A study of wind data collected from the Waglan Island anemometer (Hong Kong) during 39 tropical cyclones indicates that turbulence intensity values in excess of 20% at a reference height of 50 m are likely during extreme wind conditions in a tropical cyclone. The implied surface drag coefficient of approximately 0.01 in these extreme wind conditions is
W. H. Melbourne, D. R. Blackman
openaire   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

The 14 month wind stressed residual circulation (pole tide) in the North Sea [PDF]

open access: yes
From published research it is known that a quasi-periodic 14 month atmospheric pressure oscillation of a few tenths of a millibar exists in the region of the North and Baltic Seas.
Oconnor, W. P.
core   +1 more source

Wind-induced circulations of the black sea

open access: yesWater Science and Technology, 1995
A two-dimensional single layer hydrodynamic model of the Black Sea is constructed in which currents are driven by the forcing effect of the wind. An explicit finite difference scheme was used where the equations were discretized over a 128 × 79 non-staggered grid.
Kıran, N   +3 more
openaire   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Time dependent wind fields [PDF]

open access: yes
Two tasks were performed: (1) determination of the accuracy of Seasat scatterometer, altimeter, and scanning multichannel microwave radiometer measurements of wind speed; and (2) application of Seasat altimeter measurements of sea level to study the ...
Chelton, D. B.
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Active and passive microwave measurements in Hurricane Allen [PDF]

open access: yes
The NASA Langley Research Center analysis of the airborne microwave remote sensing measurements of Hurricane Allen obtained on August 5 and 8, 1980 is summarized.
Bahn, G. S.   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy