Results 91 to 100 of about 193,173 (339)

Discussion on Progress of Intracranial Aneurysm Interventional Therapy Instruments

open access: yesZhongguo yiliao qixie zazhi
Intracranial aneurysm is a common cerebrovascular disease with high morbidity and mortality. Endovascular interventional therapy has advantages of high efficiency and minimally invasive.
Han ZHANG, Ping LIU, Qinglong LIU
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Efficiency Improvement Strategy for Multiple Operating Points in Doubly Fed Magnetic Geared Motor

open access: yesApplied Sciences, 2020
The doubly fed magnetic geared motor, which has dual AC windings, can be operated with different frequencies in the inner and outer windings. However, the inner and outer windings have different numbers of pole pairs to meet the pole combination derived ...
Homin Shin, Junghwan Chang
doaj   +1 more source

Permanent-magnet brushless machines with unequal tooth widths and similar slot and pole numbers [PDF]

open access: yes, 2005
This paper presents a comparative study of three-phase permanent-magnet brushless machines in which the slot and pole numbers are similar, with reference to conventional brushless dc machines in which the ratio of the slot number to pole number is ...
Howe, D., Ishak, D., Zhu, Z.Q.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Multiphase induction motor drives - a technology status review [PDF]

open access: yes, 2007
The area of multiphase variable-speed motor drives in general and multiphase induction motor drives in particular has experienced a substantial growth since the beginning of this century.
Abbas   +121 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Magnetic bearing and motor [PDF]

open access: yes, 1983
A magnetic bearing for passively suspending a rotatable element subjected to axial and radial thrust forces is disclosed. The magnetic bearing employs a taut wire stretched along the longitudinal axis of the bearing between opposed end pieces and an ...
Studer, P. A.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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