Results 141 to 150 of about 193,173 (339)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Numerical Study of Multi‐Pole Generator With HTS Windings for Direct Drive Wind Turbines
IET Electric Power ApplicationsHigh‐temperature superconducting (HTS) materials show potential advantages for direct drive wind turbine generators by enabling higher power density and lower volume. However, incorporating HTS windings necessitates a cryogenic system, which can increase
Shuangrong You +5 more
doaj +1 more source
Binary magnetic memory device Patent [PDF]
, 1965 Nondestructive interrogating and state changing circuit for binary magnetic storage ...
Schaefer, D. H.
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
, 2012 Source: Herweghs Werke in drei Teilen. Herausgegeben mit Einleitungen und Anmerkungen versehen von Hermann Tardel, Berlin, Leipzig, Wien, Stuttgart: Bong & Co., [1909].
openaire +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Apparatus for measuring current flow Patent [PDF]
, 1969 Electric current measuring apparatus design including saturable core transformer and energy storage device to avoid magnetizing current errors from transformer output ...
Paulkovich, J.
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Magneto-thermally coupled field simulation of homogenized foil winding models
Advanced Modeling and Simulation in Engineering SciencesFoil windings have, due to their layered structure, different properties than conventional wire windings, which make them advantageous for high frequency applications. Both electromagnetic and thermal analyses are relevant for foil windings.
Silas Weinert +3 more
doaj +1 more source