Results 51 to 60 of about 5,459 (264)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Power transformer geometry monitoring of active parts by SFRA method [PDF]

open access: yesZbornik Radova: Elektrotehnički Institut "Nikola Tesla", 2014
During regular operation, power transformer windings are continuously exposed to electromechanical stresses and vibrations. Surges during lightning or short circuits may cause the weakening of the mechanical structure and the mechanical reinforcing parts
Ilić Denis   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The numerical method of inverse Laplace transform for calculation of overvoltages in power transformers and test results [PDF]

open access: yesSerbian Journal of Electrical Engineering, 2014
A methodology for calculation of overvoltages in transformer windings, based on a numerical method of inverse Laplace transform, is presented.
Mikulović Jovan Č.   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

ELECTRIC MACHINE WITH AXIAL MAGNETIC FLUX, PERMANENT MAGNETS AND MULTILAYERED PRINTING WINDINGS

open access: yesТехнічна електродинаміка, 2020
The use of printed windings in electric machines with permanent magnets and axial magnetic flux allows to reduce their axial size and significantly to increase the current density in the windings.
В.В. Гребеніков   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Source of magnetic fields with complex energy-frequency and polarization structure

open access: yesТехнологія та конструювання в електронній апаратурі, 2008
A method is proposed for the design synthesis of a source of rotating magnetic fields based on the combination of three mutually orthogonal solenoidal circuits powered by alternating current. The feasibility of constructing a magnetoforming system with a
N. E. Zhitnik   +4 more
doaj  

Discussion on Progress of Intracranial Aneurysm Interventional Therapy Instruments

open access: yesZhongguo yiliao qixie zazhi
Intracranial aneurysm is a common cerebrovascular disease with high morbidity and mortality. Endovascular interventional therapy has advantages of high efficiency and minimally invasive.
Han ZHANG, Ping LIU, Qinglong LIU
doaj   +1 more source

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