Results 81 to 90 of about 3,905,451 (335)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Fast Ewald summation for electrostatic potentials with arbitrary periodicity
, 2017 A unified treatment for fast and spectrally accurate evaluation of electrostatic potentials subject to periodic boundary conditions in any or none of the three space dimensions is presented.
Bagge, Joar +2 more
core +1 more source
Reservoir computing with a single time-delay autonomous Boolean node [PDF]
Physical review. E, Statistical, nonlinear, and soft matter physics, 2014 We demonstrate reservoir computing with a physical system using a single autonomous Boolean logic element with time-delay feedback. The system generates a chaotic transient with a window of consistency lasting between 30 and 300 ns, which we show is ...
N. Haynes +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Discrete Dynamics in Nature and Society, 2013 The analyzing and processing of multisource real-time transportation data stream lay a foundation for the smart transportation's sensibility, interconnection, integration, and real-time decision making.
Wang Hanning +4 more
doaj +1 more source
FALI: Time Memory Information of Windows Computer Systems [PDF]
International Journal of Intelligent Computing Research, 2013 In today digital investigation, forensic application level information (FALI) has become an important part of digital forensic research. In this research, information stored on Windows computer systems was analysed. The user input gathered from the volatile memory (RAM) of Windows applications has been described as the most important aspect of digital ...
Olajide, F, Trafford, R
openaire +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Sliding window higher-order cumulants for detection of eye blink artifact from short segments of single-channel EEG [PDF]
PeerJ Computer ScienceBackground The prevalence of single-channel electroencephalogram (EEG) is increasing. However, eye blink artifacts can contaminate EEG signals, potentially impacting their clinical utility.
Guojing Wang +5 more
doaj +2 more sources
Private Decayed Sum Estimation under Continual Observation
, 2012 In monitoring applications, recent data is more important than distant data. How does this affect privacy of data analysis? We study a general class of data analyses - computing predicate sums - with privacy.
Bolot, Jean +4 more
core +1 more source
Optimized Kaiser–Bessel Window Functions for Computed Tomography [PDF]
IEEE Transactions on Image Processing, 2015 Kaiser-Bessel window functions are frequently used to discretize tomographic problems because they have two desirable properties: 1) their short support leads to a low computational cost and 2) their rotational symmetry makes their imaging transform independent of the direction.
Masih, Nilchian +3 more
openaire +2 more sources