Results 91 to 100 of about 1,001,880 (302)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

City Lights : Windows Collective : Expanded Cinema at the Shenkman Arts Centre

open access: yes, 2016
Event catalog containing synopsis of the projected films of the City Lights : Windows Collective : Expanded Cinema at the Shenkman Arts Centre ...

core   +1 more source

Windows 2016 szerver szolgáltatásai

open access: yes, 2018
A Windows 2016 szerver szolgáltatásai. Szerepkörök bemutatása és tárgyalása. Főbb témakörök: Active Directory, virtualizáció, tárolási megoldások, biztonság. Hasonlítás a régebbi technológiákhoz. Újítások bemutatása az előző verziókhoz képest. Többszintű
Mezősi, Viktor
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

TRANSLUCENT CONSTRUCTIONS WITH CONTROLLED THERMAL CARACTERISTICS

open access: yesProblems of the Regional Energetics, 2011
There are presented results of experimental and theoretical research of new translucent constructions with controlled thermal characteristics. There are studied dependencies of thermal characteristics of windows with heat generation and aeration of via ...
Nizovtsev M.I., Terehov V.I.
doaj  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

A Brief History of Early Silica Glass: Impact on Science and Society

open access: yesSubstantia, 2019
Silicon in the form of silica is the basis of common glass and its uses predate recorded history. The production of synthetic glass, however, is thought to date back to no earlier than 3000 BCE.
Seth C Rasmussen
doaj   +1 more source

Windows 2016 szerver címtár újdonságai

open access: yes, 2019
Szakdolgozatomban szeretném bemutatni a Windows 2016 szerver címtár újdonságait a további új szolgáltatással kiegészítve. A témakörökben a Windows Server 2016 bemutatásával kezdtem. A 2.
Kiss-Tarsoly, Balázs
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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