Results 91 to 100 of about 1,671,349 (348)

What's new in Windows 11

open access: yes, 2022
A szakdolgozat Windows 11 operációs rendszerrel foglalkozik. Operációs rendszerek fejlesztése során fontosak az előzőekről való visszajelzések, ezért a Windows 11 elődei röviden bemutatásra kerülnek. Utána kezdődik maga a Windows 11 bemutatása. Szó van a
Nagy, Zsigmond Imre
core  

A unified tabu search algorithm for vehicle routing problems with soft time windows [PDF]

open access: yes, 2007
The different ways of allowing time window violations lead to different types of the vehicle routing problems with soft time windows (VRPSTW). In this paper, different types of VRPSTW are analysed.
Eglese, R W   +7 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Windows 10 újdonságai

open access: yes, 2019
Szakdolgozatomban a Windows 10 operációs rendszert és annak újdonságait mutatom be, amely a Windows operációs rendszer jelenleg legfrissebb verziója.
Jónás, Krisztián
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Hack proofing Windows 2000 /

open access: yes, 2001
The complete, authoritative guide to protecting your Windows 2000 Network "Essential reading for your IT security organization."--Deena Joyce, Director of Information Technology and Network Security, Casino Magic Pick up a newspaper or watch the evening ...
Todd, Chad., Johnson, Norris L.
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Windows virtualizációs megoldásai

open access: yes, 2015
Szakdolgozatomban a virtualizációs technológia bemutatásáról írok, kiemelt figyelemmel a Windows virtualizációs megoldásaira. Tartalmazza a virtualizáció történelmi hátterét, a Windows Hyper-V fejlődését és a piacon betöltött szerepét más virtualizációs ...
Holba, Máté László
core  

KnowledgePro windows: The order of merit? [PDF]

open access: yes, 1994
The producers of KnowledgePro look set with their latest release of KPWIN (KnowledgePro Windows) to fulfil Richard Hale‐Shaw's prophecy that it will become ‘one of the most powerful visual development environments’ (Hale‐Shaw 1992). Comparisons are drawn
Martin Reynolds, Reynolds, Martin
core   +1 more source

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