Results 91 to 100 of about 1,001,880 (302)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
City Lights : Windows Collective : Expanded Cinema at the Shenkman Arts Centre
Event catalog containing synopsis of the projected films of the City Lights : Windows Collective : Expanded Cinema at the Shenkman Arts Centre ...
core +1 more source
Windows 2016 szerver szolgáltatásai
A Windows 2016 szerver szolgáltatásai. Szerepkörök bemutatása és tárgyalása. Főbb témakörök: Active Directory, virtualizáció, tárolási megoldások, biztonság. Hasonlítás a régebbi technológiákhoz. Újítások bemutatása az előző verziókhoz képest. Többszintű
Mezősi, Viktor
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
TRANSLUCENT CONSTRUCTIONS WITH CONTROLLED THERMAL CARACTERISTICS
There are presented results of experimental and theoretical research of new translucent constructions with controlled thermal characteristics. There are studied dependencies of thermal characteristics of windows with heat generation and aeration of via ...
Nizovtsev M.I., Terehov V.I.
doaj
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
A Brief History of Early Silica Glass: Impact on Science and Society
Silicon in the form of silica is the basis of common glass and its uses predate recorded history. The production of synthetic glass, however, is thought to date back to no earlier than 3000 BCE.
Seth C Rasmussen
doaj +1 more source
Windows 2016 szerver címtár újdonságai
Szakdolgozatomban szeretném bemutatni a Windows 2016 szerver címtár újdonságait a további új szolgáltatással kiegészítve. A témakörökben a Windows Server 2016 bemutatásával kezdtem. A 2.
Kiss-Tarsoly, Balázs
core
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source

