Results 31 to 40 of about 432,760 (316)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Radio Continuum Spectra of Planetary Nebulae

Galaxies, 2018
Radio continuum emission of planetary nebulae is a rich source of information about their structure and physical parameters. Although radio emission is well studied, planetary nebulae show higher spectral indices than expected for homogeneous sphere.
Marcin Hajduk, Peter A. M. van Hoof, Karolina Sniadkowska, Andrzej Krankowski, Leszek Błaszkiewicz, Bartosz Dabrowski, Albert A. Zijlstra   +6 more
doaj   +1 more source

Generation of Non-Linear Technique Based 6 Hourly Wind Reanalysis Products Using SCATSAT-1 and Numerical Weather Prediction Model Outputs

Remote Sensing, 2023
We combined observations of ocean surface winds from Indian SCATterometer SATellite-1 (SCATSAT-1) with a background wind field from a numerical weather prediction (NWP) model available at National Centre for Medium-Range Weather Forecast (NCMRWF) to ...
Suchandra Aich Bhowmick, Maneesha Gupta, Abhisek Chakraborty, Neeraj Agarwal, Rashmi Sharma, Meer Mohammed Ali   +5 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Effects of Wind Clumping on Colliding Winds [PDF]

Symposium - International Astronomical Union, 1995
Recent studies of variable Wolf-Rayet emission lines reveal a hierarchy of structures, characterized by power laws analogous to what is expected from supersonic compressible turbulence. The collision of inhomogeneous winds can be very different from the case of smooth winds.
openaire   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

The detection dogs test is more sensitive than real-time PCR in screening for SARS-CoV-2

Communications Biology, 2021
Hag-Ali and colleagues highlight the potential for using trained dogs for detecting COVID-19 positive patients. The dogs, originally trained for explosives detection, were able to detect COVID-19 positive sweat samples with a sensitivity rivaling the ...
Mohammed Hag-Ali, Abdul Salam AlShamsi, Linda Boeijen, Yasser Mahmmod, Rashid Manzoor, Harry Rutten, Marshal M. Mweu, Mohamed El-Tholoth, Abdullatif Alteraifi AlShamsi   +8 more
doaj   +1 more source

The winding road [PDF]

Science, 2014
On a bright July day more than 3 decades ago, I turned up at the physics department of the University of Delaware (UD), Newark, hoping to meet my new research adviser. I was met instead with quizzical looks: The professor had died some months before I arrived. No one had told me. ¶ I had come a long way.
openaire   +2 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source