Results 71 to 80 of about 432,760 (316)
Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte +7 morewiley +1 more sourceIn vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni +14 morewiley +1 more sourceAdaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch +16 morewiley +1 more sourceInfluence of marine and continental processes on the dynamics of a sand-ridge at the mouth of the Mafaguaqu river (Caraguatabuba - SP): preliminary conditions</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Brazilian Journal of Oceanography</i>, 1983 </span><br><span class="r_content">This paper deals with the sedimentation and erosion dynamics of a sand-ridge on the Maçaguaçu River mouth on the São Paulo coastal plain, north of Caraguatatuba Bay. Sedimentological, climatic and hydrodynamic data were analysed from an integrative point </span><br><span class="r_sub"><i>May Christine Modenesi<span id="ma_5" style="display:none">, Moysés Gonsalez Tessler, Olga Cruz, Armando Marcio Coimbra</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_5')">+3 more</a></small></i></span><br><small><a href="https://doaj.org/article/b0777d78714443aab5454ff338ff442d" target="_blank" rel="nofollow" title="doaj.org/article/b0777d78714443aab5454ff338ff442d">doaj</a> </small> <div id="more_5" style="display:none"><a href="/sci_redir.php?doi=10.1590%2FS1679-87591983000100008" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1590/S1679-87591983000100008'); alert('Copied the doi');">copy doi</a> <small>(10.1590/S1679-87591983000100008)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_5')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.17125/gov2018.ch14" target="_blank" rel="nofollow">Wind Waves</a> <b><a href="https://diginole.lib.fsu.edu/islandora/object/fsu%3A602129/datastream/PDF/view" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16">, 2018 </span><br><span class="r_content">Wind-generated waves dominate sea surface motions for periods shorter than 300 seconds. Waves are of interest for many applications ranging from navigation safety to ocean and coastal engineering. Waves also define air-sea fluxes and have important interactions with surface currents, upper ocean turbulence, and sea ice.</span><br><span class="r_sub"><i>Ardhuin, Fabrice, Orfila, Alejandro</i></span><br><small><a href="https://explore.openaire.eu/search/publication?pid=10.17125%2Fgov2018.ch14" target="_blank" rel="nofollow" title="openaire.eu/search/publication?pid=10.17125%2Fgov2018.ch14">openaire</a> </small> <div id="more_6" style="display:none"><a href="/sci_redir.php?doi=10.17125%2Fgov2018.ch14" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="https://archimer.ifremer.fr/doc/00461/57251/" target="_blank" rel="nofollow" title="archimer.ifremer.fr/doc/00461/57251/">archimer.ifremer.fr</a><br> <a href="javascript:navigator.clipboard.writeText('10.17125/gov2018.ch14'); alert('Copied the doi');">copy doi</a> <small>(10.17125/gov2018.ch14)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_6')">+2 more sources</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/1878-0261.70129" target="_blank" rel="nofollow">Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Molecular Oncology, EarlyView.</i></span><br><span class="r_content">This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...</span><br><span class="r_sub"><i>Marco Strecker<span id="ma_7" style="display:none">, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_7')">+16 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/1878-0261.70129?mi=2or9o2m&af=R&AllField=winds&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/1878-0261.70129?mi=2or9o2m&af=R&AllField=winds&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small> <div id="more_7" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F1878-0261.70129" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/1878-0261.70129'); alert('Copied the doi');">copy doi</a> <small>(10.1002/1878-0261.70129)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_7')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.3989/scimar.04085.02A" target="_blank" rel="nofollow">Recruitment of juvenile fishes into a small temperate choked lagoon (Argentina) and the influence of environmental factors during the process</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Scientia Marina</i>, 2015 </span><br><span class="r_content">Juvenile fishes were sampled every 15 days from September 2009 to April 2010 along the marine-estuarine gradient (surf zone, estuary and a freshwater stream) of the Mar Chiquita lagoon, Argentina. The temporal variations of juvenile assemblages in spring-</span><br><span class="r_sub"><i>Daniel O. Bruno<span id="ma_8" style="display:none">, María B. Cousseau, Juan M. Díaz de Astarloa, Eduardo M. Acha</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_8')">+3 more</a></small></i></span><br><small><a href="https://doaj.org/article/b6be07ec209441069b1449389298e1ad" target="_blank" rel="nofollow" title="doaj.org/article/b6be07ec209441069b1449389298e1ad">doaj</a> </small> <div id="more_8" style="display:none"><a href="/sci_redir.php?doi=10.3989%2Fscimar.04085.02A" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.3989/scimar.04085.02A'); alert('Copied the doi');">copy doi</a> <small>(10.3989/scimar.04085.02A)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_8')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1109/jstars.2021.3087742" target="_blank" rel="nofollow">Scatterometer Sea Surface Wind Product Validation for HY-2C</a> <b><a href="https://ieeexplore.ieee.org/ielx7/4609443/9314330/09449958.pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: gold" title="open access: gold" width="16" height="16">, 2021 </span><br><span class="r_sub"><i>Zhixiong Wang<span id="ma_9" style="display:none">, Juhong Zou, Ad Stoffelen, Wenming Lin, Anton Verhoef, Xiuzhong Li, Yijun He, Youguang Zhang, Mingsen Lin</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_9')">+8 more</a></small></i></span><br><small><a href="https://openalex.org/W3171476176" target="_blank" rel="nofollow" title="openalex.org/W3171476176">openalex</a> </small> <div id="more_9" style="display:none"><a href="/sci_redir.php?doi=10.1109%2Fjstars.2021.3087742" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1109/jstars.2021.3087742'); alert('Copied the doi');">copy doi</a> <small>(10.1109/jstars.2021.3087742)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_9')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/1878-0261.70130" target="_blank" rel="nofollow">Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Molecular Oncology, EarlyView.</i></span><br><span class="r_content">This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...</span><br><span class="r_sub"><i>Joseph Saad<span id="ma_10" style="display:none">, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_10')">+17 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/1878-0261.70130?mi=2or9o2m&af=R&AllField=winds&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/1878-0261.70130?mi=2or9o2m&af=R&AllField=winds&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small> <div id="more_10" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F1878-0261.70130" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/1878-0261.70130'); alert('Copied the doi');">copy doi</a> <small>(10.1002/1878-0261.70130)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_10')">+1 more source</a></small><br></div><div class="r"><div style="margin-bottom:2px;overflow:hidden"><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-physics/" class="suggestion"onclick="show_loader();"><b>physics</b></a><br/><a href="/q-engineering/" class="suggestion"onclick="show_loader();"><b>engineering</b></a><br/><a href="/q-geology/" class="suggestion"onclick="show_loader();"><b>geology</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-meteorology/" class="suggestion"onclick="show_loader();"><b>meteorology</b></a><br/><a href="/q-environmental_science/" class="suggestion"onclick="show_loader();"><b>environmental science</b></a><br/><a href="/q-electrical_engineering/" class="suggestion"onclick="show_loader();"><b>electrical engineering</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-quantum_mechanics/" class="suggestion"onclick="show_loader();"><b>quantum mechanics</b></a><br/><a href="/q-computer_science/" class="suggestion"onclick="show_loader();"><b>computer science</b></a><br/><a href="/q-wind_speed/" class="suggestion"onclick="show_loader();"><b>wind speed</b></a><br/></div></div></div><div class="pagenav"><a href="/q-winds/p-7/" rel="nofollow"><b>previous</b></a> <a href="/q-winds/p-6/" rel="nofollow">6</a> <a href="/q-winds/p-7/" rel="nofollow">7</a> <b>8</b> <a href="/q-winds/p-9/" rel="nofollow">9</a> <a href="/q-winds/p-10/" rel="nofollow">10</a> <a href="/q-winds/p-9/" id="next" rel="nofollow"><b>next</b></a> </div><br></div>
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