Results 101 to 110 of about 450,371 (196)

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source

Surrogate Modeling of Non-Linear Folding Wing Tip Aerodynamic Coefficients

Engineering Proceedings
The development of sustainable and efficient aircraft concepts, such as those featuring flared folding wing tips (FWTs), introduces both aerodynamic and structural challenges.
Andreas Molz, Christian Breitsamter
doaj   +1 more source

Vine‐Inspired Soft Robotics: Materials, Actuations, and Emerging Applications

Advanced Science, EarlyView.
Vine‐inspired robots grow from the tip, enabling navigation through confined spaces with minimal disturbance. This Review summarizes material and actuation strategies for vine‐inspired growth, key functions including steering, retraction, attachment, branching, and variable stiffness, and emerging applications spanning medical intervention, confined ...
Jiahao Wu, Xingyun Liu, Fangzhou Wang, Huili Ren, Chaojun Zhang, Ziyu Ren, Zunqi Liu, Jing Li   +7 more
wiley   +1 more source

Notes: Interview with Henry Wing, June 7, 1924

, 1924
Interview with Henry Wing, 4 ...
Tarbell, Ida M.
core  

Design of Multi-Wing Deployment Mechanism Based on Multiple Performance Indicators and Topology: Theoretical and Experimental Study

Applied Sciences
The folding wing deployment mechanisms of aircraft are constrained by weight and space limitations, necessitating fewer actuators, multiple outputs, compact designs, and high efficiency. However, existing folding wing mechanisms often overlook the impact
Guangqing Zhai, Jianguo Tao, Hong Xiao, Hongwei Guo, Guang Yang, Runchao Zhao, Chen Yao, Rongqiang Liu   +7 more
doaj   +1 more source

Unlocking the Full Potential of Jumping Condensation on Microstructured Surfaces

Advanced Science, EarlyView.
Microcone arrays exhibit a spacing‐dependent transition between jumping and non‐jumping condensation. Dense microstructures favor full Cassie droplets, which depart cleanly, while wider spacing favors partial Cassie droplets that retain a localized wet region initiating new nucleation. These findings establish a link between microdroplet morphology and
Mariia S. Kiseleva, Tytti Kärki, Mika Latikka, Parham Koochak, Sakari Lepikko, Maja Vuckovac, Tomi Koskinen, Ramesh Raju, Ville P. Jokinen, Jiazheng Liu, Nenad Miljkovic, Jaakko V. I. Timonen, Ilkka Tittonen, Robin H. A. Ras   +13 more
wiley   +1 more source

Habitat‐Specific Design Strategies for Untethered Soft Robots

Advanced Science, EarlyView.
Habitat shapes the design of untethered soft robots. Across land, water, air, and living tissues, environmental constraints govern viable combinations of compliant structures, actuation mechanisms, and energy delivery. This review connects these constraints with robotic performance and identifies design principles for advancing adaptable, durable, and ...
Siyang Li, Zhikun Miao, Tuck‐Whye Wong, Tiefeng Li   +3 more
wiley   +1 more source

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

Advanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun, Rohan Narayan, Santhosh Kambaiah Nagaraj, Rishad Shiraz, Abinaya Kaliappan, Sumandeep Kaur, Ankur Singh, Siva Shanmugam Selvaraj, Gudepalya Renukaiah Rudramurthy, Chakenahalli Naveenkumar, Shridhar Narayanan, Radha Krishan Shandil, Shailly Tomar, Shashank Tripathi   +13 more
wiley   +1 more source

Multi-body dynamics modeling and transient characteristics analysis for a folding wing

, 2021
The investigation of modeling the time evolution of a folding wing during the morphing process and the dynamic characteristics analysis is carried out. The governing equations with uniform form are developed from the integration of floating frame method ...
Ni, Yingge, Zhang, Wei, Lv, Yi
core  

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

Advanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang, Sheng Zhang, Linxia Ouyang, Xin Du, Xin Huang, Zhilin Wang, Huixian Xie, Jiale Tang, Liyi Lou, Wenqing Ling, Weihao Wang, Jiang Zhou, Zhen Liu, Yibo Hu, Fuwen Wei, Guangping Huang   +15 more
wiley   +1 more source