Results 51 to 60 of about 25,090 (299)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Combination of Astragalus membranaceus and Euonymus alatus (THUNB.) SIEB. for treatment of diabetes: A network-based pharmacology research

open access: yesJournal of Traditional Chinese Medical Sciences, 2016
Objective: To find the target genes in combination of astragalus root (Astragalus membranaceus) and spindle tree wings (Euonymus alatus (THUNB.) SIEB.) (Qijian Heji) with the function of regulating blood glucose levels in kk mice by real-time ...
Kun Chen   +10 more
doaj   +1 more source

Exaggerated trait allometry, compensation and trade-offs in the New Zealand giraffe weevil (Lasiorhynchus barbicornis). [PDF]

open access: yesPLoS ONE, 2013
Sexual selection has driven the evolution of exaggerated traits among diverse animal taxa. The production of exaggerated traits can come at a cost to other traits through trade-offs when resources allocated to trait development are limited. Alternatively
Christina J Painting, Gregory I Holwell
doaj   +1 more source

Does IGF-1 Shape Life-History Trade-Offs? Opposite Associations of IGF-1 With Telomere Length and Body Size in a Free-Living Bird

open access: yesFrontiers in Ecology and Evolution, 2022
Hormonal pathways have been proposed to be key at modulating how fast individuals grow and reproduce and how long they live (i.e., life history trajectory).
Bibiana Montoya   +8 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Video S1 from On the autorotation of animal wings

open access: yes, 2016
Autorotation performance of wings from ten insect ...
Victor Manuel Ortega-Jimenez (801696)   +3 more
core   +1 more source

Phenotypic characterization of local female duck populations in Indonesia

open access: yesJournal of Asia-Pacific Biodiversity, 2019
Information on phenotypic traits is a prerequisite in animal genetic resource conservation and improvement. Phenotypic characteristics of 180 Indonesian female ducks collected from six populations (Alabio, Bayang, Magelang, Pegagan, Pitalah, and Rambon ...
Dyah Maharani   +4 more
doaj   +1 more source

Propelling and perturbing appendages together facilitate strenuous ground self-righting

open access: yeseLife, 2021
Terrestrial animals must self-right when overturned on the ground, but this locomotor task is strenuous. To do so, the discoid cockroach often pushes its wings against the ground to begin a somersault which rarely succeeds. As it repeatedly attempts this,
Ratan Othayoth, Chen Li
doaj   +1 more source

The essential requirement of an animal heme peroxidase protein during the wing maturation process in Drosophila [PDF]

open access: yesBMC Developmental Biology, 2017
Thus far, a handful of genes have been shown to be related to the wing maturation process in insects. A novel heme peroxidase enzyme known as curly suppressor (Cysu)(formerly CG5873), have been characterized in this report because it is involved in wing morphogenesis.
Dondra Bailey   +5 more
openaire   +2 more sources

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