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The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

open access: yesAdvanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries   +25 more
wiley   +1 more source

Winter Hardiness of Annual-Fruiting Raspberries in the South of the Irkutsk Region [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2013
The winter hardiness of different varieties of annual-fruiting raspberries in field and laboratory conditions was studied. The hardiness of annual-fruiting raspberry, mow culture and two-year shoots was assessed. We select the most winter-hardy genotypes
Rachenko, M. A., Rachenko, E. I.
doaj  

Promising source material for winter triticale breeding under the conditions of the Middle Urals

open access: yesТруды по прикладной ботанике, генетике и селекции, 2022
Background. The northern border of cereal crop cultivation passes through the territory of Sverdlovsk Province. Cultivars of winter triticale developed in the regions of Russia located to the south are grown there, but they die under unfavorable winter ...
G. N. Potapova   +3 more
doaj   +1 more source

Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu   +13 more
wiley   +1 more source

Cold hardiness research on agricultural and horticultural crops in Finland

open access: yesAgricultural and Food Science, 2008
This paper represents an overview of cold hardiness research conducted on agricultural and horticultural crops, as well as on amenity plants in Finland. Inadequate freezing tolerance and/or winter hardiness often prevents introduction of new species and ...
L. LINDÉN, M. SEPPÄNEN, A. VÄINÖLÄ
doaj  

Multi‐Scale Bionic Structure Constructs Biomass Flame‐Retardant Thermal Insulation Foam Material

open access: yesAdvanced Science, EarlyView.
Inspired by mussel adhesion and hierarchical brick‐and‐mortar architectures, a cellulose‐based biomimetic foam is constructed by anchoring bentonite nanosheets onto a polydopamine‐decorated cellulose nanofiber network. The resulting foam combines low thermal conductivity with intrinsic flame retardancy and full biodegradability, presenting a ...
Jianming Liao   +10 more
wiley   +1 more source

Comparison of winter hardiness components in Fragaria L. accessions with different phenorhythmotypes in an artificial climate chamber

open access: yesТруды по прикладной ботанике, генетике и селекции
Background. Overwintering is a critical factor for strawberry cultivation in Russia. Those Fragaria L. spp. that grow in the Asian regions of Russia with an extreme continental climate, which have so far been little studied and are poorly involved in ...
A. A. Kharchenko, L Yu. Novikova
doaj   +1 more source

Advancing Energy Efficiency in Smart Windows via Dual‐Responsive Electro‐Thermochromism

open access: yesAdvanced Science, EarlyView.
A durable and stable quasi‐solid‐state electro‐thermal dual‐responsive photothermal regulation device has been employed in advanced energy‐efficient smart windows. The devised device not only incorporates a thermochromic hydrogel characterized by high ionic conductivity, high optical transmittance, and a low LCST, but also comprises an electrochromic ...
Tongyu Chen   +10 more
wiley   +1 more source

Identification of Candidate Genes for Winter Hardiness in Chickpea [PDF]

open access: yes, 2023
Chickpea (Cicer arietinum L.) is a highly profitable crop due to its high dietary protein content and fiber, critical minerals, and excellent capability to fix atmospheric nitrogen, especially in low-cost food production systems.
Ekinci, Ozge
core   +1 more source

TiO6 as a Compensatory Structural Unit in Co‐Free, High‐Ni Layered Oxide for Durable Lithium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
Ti substitution stabilizes Co‐free high‐Ni layered oxides through both structural and electronic effects. TiO6 octahedra act as compensatory structural units that help interrupt cooperative Jahn–Teller distortion and suppress detrimental phase transitions, while the electron‐withdrawing inductive effect of Ti stabilizes the oxygen lattice. As a result,
Bixian Ying   +19 more
wiley   +1 more source

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