Results 251 to 260 of about 12,862 (289)

Oral paltusotine, a nonpeptide selective somatostatin receptor 2 agonist: Mass balance, absolute bioavailability and metabolism in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 2070-2079, July 2025.
Abstract Aims Paltusotine is a novel, nonpeptide, selective somatostatin receptor 2 agonist in development for the treatment of acromegaly and carcinoid syndrome. This study investigated the mass balance, routes of excretion, absolute bioavailability and metabolite profile of orally administered paltusotine.
Rosa Luo   +6 more
wiley   +1 more source

A Hybrid Method Using Slime Mold Algorithm and Genetic Algorithm for Feature Selection Problems in Intrusion Detection Systems

open access: yesEngineering Reports, Volume 7, Issue 7, July 2025.
In this paper, the slime mold algorithm (SMA) and genetic algorithm (GA) as metaheuristic algorithms are combined to create a novel hybrid intrusion detection (ID) method considering feature selection for classification problems. The effectiveness of this suggested approach is also evaluated in comparison to other well‐known methods like GA, PSO, GOA ...
Soodeh Hosseini   +2 more
wiley   +1 more source

Cargo Analysis and MRI‐Based Therapeutic Assessment of Iron Oxide Labelled Extracellular Vesicles of Hypoxia Human Stem Cells in Ischemic Stroke

open access: yesJournal of Extracellular Biology, Volume 4, Issue 7, July 2025.
ABSTRACT Human mesenchymal stem cells (hMSCs) have been under investigation in preclinical and clinical settings for treating neurological disorders in recent years. Predominantly due to paracrine effects in vivo, hMSC‐secreted extracellular vesicles (EVs) are at the forefront of these investigations.
Shannon Helsper   +7 more
wiley   +1 more source

A novel feature-oriented quality of anything (QoX) framework for end-to-end robotic services in 6G networks. [PDF]

open access: yesSci Rep
Mineeva V   +6 more
europepmc   +1 more source

Evaluating occurrence and abundance of displaying male American woodcock (Scolopax minor) north of the current Singing‐Ground Survey range

open access: yesThe Journal of Wildlife Management, Volume 89, Issue 5, July 2025.
The American Woodcock Singing‐Ground Survey (SGS) may not cover all available woodcock breeding range, particularly in more northern regions. Using SGS data collected in Canada between 2000 and 2019, we evaluated the relationship between 16 landscape covariates and male woodcock occurrence and abundance and we developed a predictive map to identify ...
Kristin Bianchini   +3 more
wiley   +1 more source

White‐tailed deer behaviors at three forage settings: Implications for transmission of chronic wasting disease

open access: yesThe Journal of Wildlife Management, Volume 89, Issue 5, July 2025.
We evaluated deer contact rates at 3 common feed settings. Contacts included direct (deer to deer), environmental (deer to environment), and self (deer to self). Contacts among deer were higher at bait sites for all contact types. Abstract Chronic wasting disease (CWD) is induced by a protein found in cervid brains called prions that cause folding of ...
Samantha E. Courtney   +7 more
wiley   +1 more source

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