Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Deploying a Wireless Sensor Network to Track Pesticide Pollution in Kiu Wetland Wells: A Field Study. [PDF]
Mutunga T +3 more
europepmc +1 more source
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley +1 more source
An Innovative Linear Wireless Sensor Network Reliability Evaluation Algorithm. [PDF]
Ma T, Guo H, Li X.
europepmc +1 more source
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source
Comprehensive electrical models for a wireless sensor network device. [PDF]
León Ávila BY +4 more
europepmc +1 more source
A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu +7 more
wiley +1 more source
Acoustic Source Localization Based on the Two-Level Data Aggregation Technology in a Wireless Sensor Network. [PDF]
Feng Y, Hu G, Hong L.
europepmc +1 more source
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei +11 more
wiley +1 more source
Optimisation of Sensor and Sensor Node Positions for Shape Sensing with a Wireless Sensor Network-A Case Study Using the Modal Method and a Physics-Informed Neural Network. [PDF]
Meyer Zu Westerhausen S +3 more
europepmc +1 more source

