Results 221 to 230 of about 281,017 (295)

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

Advanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo, Qianqian Zhang, Chenhao Wang, Zhiheng Yi, Alex Jinpeng Wang, Jing Tang, Min Li   +6 more
wiley   +1 more source

Clinical pearls and pitfalls in inborn errors of immunity: An expert-derived framework for diagnostic pattern recognition. [PDF]

Pediatr Allergy Immunol
Vásquez Echeverri E, Bustamante-Ogando JC, Castano-Jaramillo LM, Vélez Tirado N, Venegas Montoya E, Gómez Tello H, Palma A, Guaní-Guerra E, Ale H, Yamazaki-Nakashimada MA, Sullivan KE, Lugo Reyes SO.   +11 more
europepmc   +1 more source

Universal Battery Capacity Degradation Forecasting Driven by Foundation Models Across Diverse Chemistries and Conditions

Advanced Science, EarlyView.
A unified time‐series forecasting framework learns transferable battery capacity‐degradation patterns from 20 heterogeneous datasets spanning chemistries, formats, temperatures, and cycling conditions. A single model delivers competitive predictions on both known and previously unseen datasets, while physics‐guided representation learning improves ...
Joey Chan, Huan Wang, Zhen Chen, Haoyu Pan, Wei Wu, Zirong Wang, Ershun Pan, Min Xie, Lifeng Xi   +8 more
wiley   +1 more source

Challenging the Conventional Wisdom Around Doxorubicin in Soft Tissue Sarcoma. [PDF]

JCO Oncol Pract
Stein JN, Woodcock MG, Chen KY.
europepmc   +1 more source

Unveiling a Near‐Total Rear Passivation for High Performance of Ultra‐Thin ACIGS

Advanced Science, EarlyView.
Ultra‐thin solar cells of (Ag,Cu)(In,Ga)Se2 (ACIGS) suffer from rear interface recombination, limiting their performance. To tackle it, a full coverage plasma enhanced chemically vapor‐deposited 8 nm porous SiOx passivation layer was implemented and evaluated. It is shown that a combination of the near‐complete passivation from silica and the formation
Xavier L. Pinheiro, António J. N. Oliveira, André F. Violas, Kevin Oliveira, Paulo A. Fernandes, Marika Edoff, Pedro M. P. Salomé, Jennifer P. Teixeira   +7 more
wiley   +1 more source

Quality, reliability, and content completeness of Chinese-language short videos on impacted wisdom teeth on TikTok and Bilibili: a cross-sectional study. [PDF]

BMC Oral Health
Cai F, Zou J, Gao W.
europepmc   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source

AI Agents and the Future of Clinical Judgment in Medical Education: Opportunities, Challenges, and the Need for Human-Centered Integration. [PDF]

Health Sci Rep
Ahmady S, Kohan N, Monajemi A.
europepmc   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Advanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou, Shu Ding, Zhenyi Zhang, Qiaoling Shangguan, Jie Qiao, Peijie Zhou, Yidong Chen   +6 more
wiley   +1 more source

Exploring patient and NHS staff acceptability of artificial intelligence-supported surgical wound monitoring within the WISDOM feasibility study: a multi-centre qualitative interview study. [PDF]

BMJ Open
Tanner J, Rochon M, Cariaga K, Harris R, Beckhelling J, Bouttell J, Bolton S, Wilson K, Jurkiewicz J, Dhoonmoon L, Mostafa N, Dummer J, Basilio K, Magboo R, Procter K, McMillan C.   +15 more
europepmc   +1 more source