Results 241 to 250 of about 433,567 (330)

Aphrodisiac studies of Pavetta crassicaulis Bremek. leaf, flower extract and it pure compounds using Wistar albino rats

, 2018
R Ashwathanarayana, Raja Naika
openalex   +1 more source

Drug discovery and preclinical testing of drug candidates for developmental and epileptic encephalopathies

Epilepsia, EarlyView.
Abstract Drug development for developmental and epileptic encephalopathies (DEEs) follows different strategies on one hand including disease‐targeting precision medicine approaches considering the genetic variants and pathomechanisms in DEEs and on the other hand including therapeutic approaches with novel targets or second‐generation drug candidates ...
Heidrun Potschka, Daniel Pérez‐Pérez
wiley   +1 more source

1101 Activation of myeloid cells suppresses metastatic ovarian cancer via tumoricidal neutrophils and IL-27-secreting macrophages

Journal for ImmunoTherapy of Cancer, 2023
Nan Zhang, Toshitha Kannan, Andrew Kossenkov, Taito Miyamoto, Brennah Murphy, Bryan Manning, Daniel Claiborne, Rugang Zhang   +7 more
doaj   +1 more source

Comparative analysis of autonomic effects of ketamine-xylazine in normotensive and hypertensive rats. [PDF]

Braz J Med Biol Res
Santos PS, Pereira Júnior JL, Araújo SSP, Silva JAD, Silva AFMD, Assunção JGV, Silva RG, Oliveira AA, Nunes FVS, Noleto MS, Oliveira AP, Soriano RN, Branco LGS, Salgado HC, Sabino JPJ.   +14 more
europepmc   +1 more source

Gambaran Histopatologik Hati Tikus Wistar yang Diberikan Sari Buah Naga Merah (Hylocereus polyrhisus) dan Parasetamol

, 2018
Maurin Wowor, Lily Loho, Poppy M. Lintong   +2 more
openalex   +2 more sources

PAC‐FOS: A novel translational concordance framework identifies preclinical seizure models with highest predictive validity for clinical focal onset seizures

Epilepsia, EarlyView.
Abstract Objective Central to the development of novel antiseizure medications (ASMs) is testing of antiseizure activity in preclinical models. Although various well‐established models exist, their predictive validity across the spectrum of clinical epilepsies has been less clear.
Lyndsey L. Anderson, Kristopher M. Kahlig, Melissa L. Barker‐Haliski, Lillian G. Matthews, Hamish D. Toop, Brian Hannigan, Jacqueline French, H. Steve White, Marcio Souza, Steven Petrou   +9 more
wiley   +1 more source

Dietary methionine depletion and hydrogen sulfide-producing genes in perivascular adipose tissue of male Wistar rats. [PDF]

Physiol Rep
Corken A, Lee D, Wahl EC, Sikes JD, Thakali KM.   +4 more
europepmc   +1 more source

Effect of Different Doses of Sea Buckthorn (Hippophae rhamnoides L.) Seed Extract (Oil) on Histology of Islets of Langerhan of Pancreas in Alloxan Induced Diabetic Male Wistar Rats

Shagufta Nasreen
openalex   +2 more sources

Effects of cell therapy on seizures in animal models of epilepsy: Systematic review and meta‐analysis

Epilepsia, EarlyView.
Abstract This study was undertaken to systematically evaluate the efficacy of cell therapy in reducing seizures in animal models of chronic epilepsy. Three databases, Ovid MEDLINE, Ovid Embase, and Web of Science, were searched using predetermined eligibility criteria.
Afaf S. Altalhi, Muhammad S. Javaid, Nigel C. Jones, Kim L. Powell, Patrick Kwan, Terence J. O'Brien, Ana Antonic‐Baker   +6 more
wiley   +1 more source

Hypoglycemic and Hypolipidemic Effects of <i>Leonotis mollisima</i> Aqueous Leaf Extract in Type 2 Diabetic Rats. [PDF]

J Exp Pharmacol
Stephen N, Odoma S, Salihu TS, Joshua AO, Timothy N.   +4 more
europepmc   +1 more source