Results 301 to 310 of about 433,567 (330)
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Endocardial Schwannomas in the Wistar Rat
Journal of Veterinary Medicine Series A, 2005SummaryEndocardial neoplasms were observed in 13 Wistar rats, 15–30 months old, from a 30‐month inhalation study. Eight of the rats were dissected at 30 months and the other five between 15 and 29 months. Histologically, the lesions in the heart were diagnosed as endocardial schwannomas.
A, Teredesai, T, Wöhrmann
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Genotoxicity of nimesulide in Wistar rats
Drug and Chemical Toxicology, 2013It is mandatory for all new drugs to be tested for their potential genotoxicity in addition to general toxicity testing. Some old drugs have not been tested adequately for their genotoxic effects because these were in use before the local regulations were enforced. According to the material safety database, the toxicological effect of nimesulide is not
Debojyoti, Borkotoky +3 more
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KETAMINE’S EFFECTS ON ADOLESCENT FEMALE WISTAR- KYOTO AND WISTAR RATS
2023According to the National Institute of Mental Health (NIMH, 2021), the estimated prevalence of major depressive disorder among adolescent females, is 25.2%. Currently, pharmacological treatments for adolescents are limited. Ketamine has been shown to produce rapid and robust effects in adults with major depression.
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Spontaneous Immunoglomerulonephritis in Wistar Rats
Pathology - Research and Practice, 1980A strain of rats bred at the Nuclear Study Center of Mol (C.E.N.) develops a nephropathy characterized by granular deposition of immunoglobulin and complement in the renal glomeruli and tubules. We have attempted to specify the complement activation pathways (classical or alternate) in this disease by looking for their initial components (C1q, C3 and ...
A, Fridman-Manduzio +2 more
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METABOLISM OF MYOSMINE IN WISTAR RATS
Drug Metabolism and Disposition, 2005The alkaloid myosmine is present not only in tobacco products but also in various foods. Myosmine is easily nitrosated, yielding 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB) and the esophageal tobacco carcinogen N'-nitrosonornicotine. Due to its widespread occurrence, investigations on the metabolism and activation of myosmine are needed for risk ...
Wolfgang, Zwickenpflug +2 more
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Clinical and Experimental Hypertension. Part A: Theory and Practice, 1987
In spontaneously hypertensive rats (SHR) a diminished responsiveness for nociceptive stimuli is present, which might be associated with alterations in endogenous opioid peptide and receptor systems. In SHR, normotensive Wistar-Kyoto controls (WKY) and in Wistar rats the effects of acute morphine administration on pain sensitivity and body temperature ...
J M, Sitsen, F P, Nijkamp, W, de Jong
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In spontaneously hypertensive rats (SHR) a diminished responsiveness for nociceptive stimuli is present, which might be associated with alterations in endogenous opioid peptide and receptor systems. In SHR, normotensive Wistar-Kyoto controls (WKY) and in Wistar rats the effects of acute morphine administration on pain sensitivity and body temperature ...
J M, Sitsen, F P, Nijkamp, W, de Jong
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A supernumerary forelimb in a Wistar rat
Laboratory Animals, 1987A fifth limb, quite independent of the others, was found in a pup born in our colony of Wistar rats. The malformation is described.
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2018
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Investigatory behavior of a novel conspecific by Wistar Kyoto, Wistar and Sprague-Dawley rats
Brain Research Bulletin, 2000The assumption was made that investigatory behaviors (i.e., ano-genital and general body sniffing) of a female conspecific by a mature male rat, has positive hedonic characteristics. Because reduced interest in pleasurable events (i.e., anhedonia) is diagnostically related to depressive behavior, the hypothesis was advanced that less investigatory ...
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