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Venule distension properties in Wistar, Wistar-Kyoto, and spontaneously hypertensive rats
American Journal of Physiology-Heart and Circulatory Physiology, 1987The purpose of this study was to determine whether venule distension characteristics are modified in denervated venules in the spontaneously hypertensive rat (SHR) during the developmental stage of hypertension. The distension of denervated first-order venules (1V) and small collecting veins (SCV) in the intestine of 7- to 8-wk-old SHR, Wistar-Kyoto ...
D. J. Lang, B. L. Johns
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Wistar Kyoto and Wistar rats differ in the affective and locomotor effects of nicotine
Physiology & Behavior, 2008Anhedonia is a characteristic of clinical depression and has been associated with dysfunction of the mesolimbic dopaminergic system, a system also involved in mediating nicotine reward. To further examine the relationship between anhedonia, clinical depression and nicotine reward, the present experiment determined if Wistar Kyoto (WKY) rats, an animal ...
Isaac J. Zentner +3 more
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Wistar rat dermis recellularization
Research in Veterinary Science, 2020Skin lesions are normal to all species, regardless of gender or age. The skin, the largest organ of the body, has function as a primary barrier to the chemical, physical and biological aggressions of the environment. In animals, these lesions may be due to fights and/or predations, also as in humans, there is a very common cause of dermal lesions that ...
Gustavo de Sá Schiavo Matias +4 more
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KETAMINE’S EFFECTS ON ADOLESCENT FEMALE WISTAR- KYOTO AND WISTAR RATS
2023According to the National Institute of Mental Health (NIMH, 2021), the estimated prevalence of major depressive disorder among adolescent females, is 25.2%. Currently, pharmacological treatments for adolescents are limited. Ketamine has been shown to produce rapid and robust effects in adults with major depression.
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Ameloblastoma in a female Wistar rat
Experimental and Toxicologic Pathology, 1995A spontaneous ameloblastoma of the right mandible is described in a 120-week-old female Wistar rat (strain Chbb: THOM). The tumour had a locally aggressive growth pattern and was histologically characterized by sheets and islands of odontogenic epithelium bounded by a palisaded layer of ameloblast-like cells. Because of multifocal keratinizing squamous
Dumitru Mirea, Heinrich Ernst
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Genotoxicity of nimesulide in Wistar rats
Drug and Chemical Toxicology, 2013It is mandatory for all new drugs to be tested for their potential genotoxicity in addition to general toxicity testing. Some old drugs have not been tested adequately for their genotoxic effects because these were in use before the local regulations were enforced. According to the material safety database, the toxicological effect of nimesulide is not
Subas Chandra Parija +3 more
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