Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Input Sources and Properties of Position-Sensitive Oculomotor Fibres in the Rock Lobster, Panulirus Interruptus (Randall) [PDF]
Sets of head-up, head-down, eye-up and eye-down motor fibres were studied in the oculomotor nerve of the rock lobster. An eye-withdrawal fibre was also investigated.
Wiersma, C. A. G. +2 more
core
Copper catalysts introduced with different non‐metallic elements regulating the coordination number of Cu are prepared by magnetron sputtering. Reducing the Cu coordination number enhances C─C coupling and boosts C2+ product selectivity, by lowering the energy barrier for the *CO → *CHO conversion step. The optimized Si‐doped Cu catalyst achieves a C2+
Xiaoye Du +8 more
wiley +1 more source
A Survey of Housing Equity Withdrawal and Injection in Australia [PDF]
Over the past decade or so, aggregate data suggest a trend increase in housing equity withdrawal in Australia, potentially stimulating household spending.
Carl Schwartz +3 more
core
This review explores functional and responsive materials for triboelectric nanogenerators (TENGs) in sustainable smart agriculture. It examines how particulate contamination and dirt affect charge transfer and efficiency. Environmental challenges and strategies to enhance durability and responsiveness are outlined, including active functional layers ...
Rafael R. A. Silva +9 more
wiley +1 more source
SPLIT HALF RELIABILITY OF MODIFIED HAND TEST
Objective: To establish psychometrics of main study entitled “Adaptation, Modification and Development of Norms of Hand Test in Pakistan.” Study Design: Cross sectional study.
Fayyaz Ahmed Anjum +2 more
doaj
Nearly optimal asset allocations in retirement [PDF]
An important and frequently studied question for retirees is: what is the optimal asset allocation during retirement? This article provides a brief but simple message that conservative asset allocations in retirement are quite acceptable after all.
Pfau, Wade Donald
core +1 more source
Effects of transcutaneous auricular vagus nerve stimulation at left cymba concha on experimental pain as assessed with the nociceptive withdrawal reflex, and correlation with parasympathetic activity [PDF]
Hirotake Yokota +11 more
openalex +1 more source
Residual Venous Obstruction, alone and in Combination with D-Dimer, as a Risk Factor for Recurrence after Anticoagulation Withdrawal following a First Idiopathic Deep Vein Thrombosis in the Prolong Study [PDF]
Benilde Cosmi +8 more
openalex +1 more source
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria +7 more
wiley +1 more source

