Results 181 to 190 of about 1,405,336 (345)

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang, Jihana Achour, Laila Emam, Younes Louaguenouni, Catherine Cailleau, Françoise Mercier‐Nomé, Séverine Domenichini, Claudine Delomenie, Sezen Gul, Juliette Vergnaud, Nicolas Tsapis, Arnaud Mansart, Djillali Annane, Francois Fay, Elias Fattal   +14 more
wiley   +1 more source

Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro

Advanced Healthcare Materials, EarlyView.
A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski, Svenja Nellinger, Franziska Brigitte Albrecht, Petra Juliane Kluger   +3 more
wiley   +1 more source

Nicotine Withdrawal Drives Aversive Behaviors by Recruiting Inhibitory Interpeduncular Nucleus Inputs to the Laterodorsal Tegmentum in Mice. [PDF]

J Neurosci
Monical A, McGehee DS.
europepmc   +1 more source

Modelling New Zealand Consumption Expenditure over the 1990s [PDF]

This paper presents two models of consumption for the primary purpose of forecasting consumption expenditure growth in New Zealand. The models, which are consistent with a range of consumption functions including the life-cycle and permanent income ...
Khoon Lek Goh, Richard Downing
core  

Review of waterpower withdrawals in Middle Fork Willamette River Basin, Oregon [PDF]

, 1961
David Neal
openalex   +1 more source

A Deployable 4D Printed, Mucoadhesive and Magnetically Guided Patch for Local Therapy of Gastric Cancer

Advanced Healthcare Materials, EarlyView.
A new perspective for treatment of gastric cancer is proposed utilizing 4D printing to develop shape morphing, deployable, and magnetically guided local drug releasing patches. The deployed patches are envisioned to adhere at the tumor site to locally deliver high drug amounts.
Dina B. Mahmoud, Martin Börner, Christian Wölk, Michaela Schulz‐Siegmund   +3 more
wiley   +1 more source

Steroid Use in ABO-Incompatible Kidney Transplants: Withdrawal vs Maintenance. [PDF]

Ann Transplant
Shin DH, Kim JT, Kim SH, Park K, Kim DG, Lee JY.   +5 more
europepmc   +1 more source

Review of waterpower withdrawals in Weiser River Basin, Idaho [PDF]

, 1964
J.L. Colbert, Loyd L. Young
openalex   +1 more source

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

Evidence on antidepressant withdrawal: an appraisal and reanalysis of a recent systematic review. [PDF]

Psychol Med
Moncrieff J, Hobday H, Sørensen A, Read J, Plöderl M, Hengartner M, Kamp C, Jakobsen J, Juul S, Davies J, Horowitz M.   +10 more
europepmc   +1 more source