Results 41 to 50 of about 96,847 (281)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Study relationship between psychological between psychological dimensions of NIORDC with managers' dysfunctions and personality characteristics [PDF]
رویکردهای نوین آموزشی, 2011 The purpose of this research was to investigate the relationship between psychological dimensions of National Iranian Oil Refining & Distribution Company-Tehran's 3 units- with managers' dysfunctions and personality characteristics from employees' points
F. Fazelli, H.R. Oreyzi, H. Samavatyan
doaj
Thermal degradation of azobenzene dyes
Results in Chemistry, 2020 Ten azobenzene dyes were tested for their thermal degradation products from ambient temperature to 800 °C using a thermogravimetric technique. Degradation products were analyzed at each 100 °C increment using gas chromatography-mass spectrometry ...
Thao L. Nguyen, Mahmoud A. Saleh
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
End-of-life ethical dilemmas in intensive care unit
Zdravniški Vestnik, 2013 Sustaining vital functions in critically ill in the ICU frequently allows prolongation of patient’s life even in circumstances where the treatment has lost its medical rationale and/or there is no hope for the patient’s condition to improve.
Štefan Grosek +3 more
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High Temperature Materials and Processes, 2012 The single crystal nickel-based superalloys with different dendrite spacings were prepared by using various withdrawing rates, and the influence of withdrawing rates on elements segregation and creep properties of them is investigated through creep ...
Tian Sugui +4 more
doaj +1 more source
The Principle of Proportionality: Foregoing/Withdrawing Life Support
South African Family Practice, 2005 No abstract available.
D. Knapp van Bogaert, G.A. Ogunbanjo
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source