Results 221 to 230 of about 12,190,982 (354)

Intentionally hastening death by withholding or withdrawing treatment [PDF]

open access: bronze, 2006
Georg Bosshard   +4 more
openalex   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

open access: yesChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel   +5 more
wiley   +1 more source

Religion and Regulatory Variance: Halal Regimes as Islamic Public Administration

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT One quarter of humanity are Muslims, for whom halal food is an everyday consideration. The global food system has made assessing food products nearly impossible for consumers, requiring elaborate regulatory regimes. This article analyzes halal regulation as a notable example of Islamic public administration (IPA), as an application of ...
Logan Cochrane   +2 more
wiley   +1 more source

Islamic Public Administration in Practice: The Taliban's “Gender Apartheid” Governance in Afghanistan

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT This article analyzes the Taliban's post‐2021 governance model through the Islamic Public Administration (IPA) framework, focusing on justice, equality, and women's inclusion. It asks: (1) How does the Taliban's governance align with core IPA principles?
Parwiz Mosamim   +1 more
wiley   +1 more source

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