Results 71 to 80 of about 1,072,260 (332)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Critical Social Justice: The Moral Imperative for Critical Perspectives in Nursing

open access: yesWitness, 2019
There is increasing urgency to enact critical perspectives in the profession of nursing, with a resurgence of the political, a deliberative focus on social change, and a growing uneasiness with remaining neutral in the face of such pressing need.
Elizabeth McGibbon, Sionnach Lukeman
doaj   +1 more source

The Fifth Amendment: If an Aid to the Guilty Defendant, an Impediment to the Innocent One [PDF]

open access: yes, 1989
The fifth amendment\u27s privilege not to answer, critics carp, insulates the guilty defendant from revealing his complicity. While this is true, ironically it also can shackle the innocent defendant from attempting to prove that another person committed
Tague, Peter W.
core   +1 more source

Secret-Sharing for NP [PDF]

open access: yes, 2014
A computational secret-sharing scheme is a method that enables a dealer, that has a secret, to distribute this secret among a set of parties such that a "qualified" subset of parties can efficiently reconstruct the secret while any "unqualified" subset ...
A. Beimel   +20 more
core   +4 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Relations between Entanglement Witnesses and Bell Inequalities

open access: yes, 2005
Bell inequalities, considered within quantum mechanics, can be regarded as non-optimal witness operators. We discuss the relationship between such Bell witnesses and general entanglement witnesses in detail for the Bell inequality derived by Clauser ...
Bruss, D.   +3 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Witness Sets

open access: yes, 2008
Given a set C of binary n-tuples and c in C, how many bits of c suffice to distinguish it from the other elements in C? We shed new light on this old combinatorial problem and improve on previously known bounds.
Hugues Randriam   +2 more
openaire   +3 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Kaskitamasowin miýw-āyāwin

open access: yesWitness, 2020
The following is a poetic re-presentation of Madeline Dion Stout’s (2012) editorial: Ascribed Health and Wellness, Atikowisi Miýw-āyāwin, to Achieved Health and Wellness, Kaskitamasowin Miýw-āyāwin: Shifting the Paradigm.
Vanessa Van Bewer
doaj   +1 more source

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