Results 61 to 70 of about 2,235,444 (190)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Law of Criminal Informant in Ethiopia

Mizan Law Review, 2019
Many jurisdictions use criminal informants –suspects or defendants who provide evidence in return to a charge or a sentence benefit– to investigate and prosecute mainly organized crimes. Ethiopia has also embraced this investigation and prosecution tool
Alemu Meheretu Negash
doaj   +1 more source

Legal Regulation of Witness Protection in the European Union [PDF]

, 2019
To effectively fight organized crime and terrorism, law enforcement agencies have to rely more and more on witness statements, since traditional investigative measures have proven less effective.
van Lent, Yorik
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Multipurpose Protection for Numeric Data With Capabilities of Self-Authentication and Ownership Declaration

IEEE Access, 2018
A new multipurpose protection method for numeric data with double capabilities of self-authentication and ownership declaration is proposed. The proposed method embeds an elaborate right witness, which is derived from (k, n)-threshold method with a ...
Che-Wei Lee
doaj   +1 more source

Greetings From Witness Protection! [PDF]

, 2018
Nicki Demere, a foster-child, is offered a position as the daughter in a family placed in Witness Protection. She disappears with her new family to North Carolina, becoming Charlotte Trevor.
Harris, Taylor
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Right to Cross-Examination and Witness Protection in Ethiopia: Comparative Overview

Mizan Law Review, 2018
Cross-examination particularly in the context of criminal trial is a human right recognized in international human rights law and the Ethiopian constitution.
Tadesse Melaku
doaj   +1 more source

Witness protection in criminal proceedings

, 2021
Předmětem práce je komplexní výklad problematiky ochrany svědků. Její autor se v ní nejprve zabývá důvody, proč by měla být ochrana svědka v právním řádu upravena, načež navazuje historií české úpravy ochrany.
Hajšman, Václav
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source