Results 51 to 60 of about 2,932,464 (305)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Sufentanil Sublingual for Acute Post-Operative Pain: A Systematic Literature Review Focused on Pain Intensity, Adverse Events, and Patient Satisfaction

Pain and Therapy, 2020
Context Pain is commonly experienced among patients after surgical procedures. Clinical pain management after surgery is far from being successful.
Luca G. Giaccari, Francesco Coppolino, Caterina Aurilio, Valentina Esposito, Maria Caterina Pace, Antonella Paladini, Maria Beatrice Passavanti, Vincenzo Pota, Pasquale Sansone   +8 more
doaj   +1 more source

Measuring Responses to Commercials: A Projective-Elicitation Approach [PDF]

, 2006
Photoelicitation and projective assessment are research methods derived from visual sociology and psychoanalysis respectively. This study combined the methods by having respondents view a commercial, and then showing them one of two versions of a ...
Soley, Lawrence
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Retrospectively investigating the 12-year experience of prenatal diagnosis of small supernumerary marker chromosomes through array comparative genomic hybridization

Taiwanese Journal of Obstetrics & Gynecology, 2019
Objective: This study retrospectively evaluated the incidences of small supernumerary marker chromosomes (sSMCs) in prenatal diagnoses and detected with gain of pathogenic copy number variation through array comparative genomic hybridization (CGH) in a ...
Min-Hui Huang, Cagge Lee, Jia-Shyuhn Chang, Han-Chow Wang, Hui-Ling Lai, Chu-Chu Chang, Tzu-Wang Chen, Yu-Fen Li, Ting-Tse Lin, Chih-Yun Yang, Shu-Peng Ho   +10 more
doaj   +1 more source

Woman-Not-Woman

Religion and Gender
Abstract During the yearly patronal festival las fiestas en honor a Santiago Apóstol ( las fiestas ), men from Loíza, Puerto Rico, transform themselves to become madwomen whose ribald and bawdy behaviour transgresses personal and ...
openaire   +1 more source

The Casual Dress of the 1950s Woman and the Casual Dress of Today\u27s Woman [PDF]

, 2019
The casual dress of American women has changed dramatically from the 1950s to the present. In the 1950s, the style was undeniably feminine, with fitted waists and full skirts ending below the knee.
Woolsey, Joanna
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Prevalence of tuberculosis in migrant children in Switzerland and relevance of current screening guidelines

Swiss Medical Weekly, 2020
AIMS Since 2016, Swiss guidelines recommend screening of all migrant children
Myriam Boukamel, Yves Fougère, Mario Gehri, Joan Carles Suris, Isabelle Rochat, Damien Miletto, Spyridoula Kyrilli, Athina Fouriki, Pierre Alex Crisinel   +8 more
doaj   +1 more source