Results 141 to 150 of about 47,215 (244)

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin   +17 more
wiley   +1 more source

When choice is not performative: the struggle for agency among women accessing family planning services in Senegal. [PDF]

open access: yesFront Glob Womens Health
Gonzalez-Capella T   +7 more
europepmc   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Harnessing Li‐Ion Binding Energy for Solvation‐Guided Electrolyte Additive Design and Robust Solid Electrolyte Interphase Reinforcement

open access: yesAdvanced Science, EarlyView.
A solvation‐guided design strategy for electrolyte additives is established, identifying Li‐ion binding energy as a crucial determinant for effective interface reinforcement. ABSTRACT The rational design of electrolyte systems is essential for stabilizing the electrode−electrolyte interface to enhance the electrochemical performance of lithium‐ion ...
Jooeun Byun   +6 more
wiley   +1 more source

Linguistic Manoeuvres: Obstetric Violence Camouflages Harm and Loss of Consent From Birth. [PDF]

open access: yesMed J Aust
Kumar-Hazard B   +5 more
europepmc   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

Perceived Time Shapes Physical Fatigue Accumulation and Its Neural Oscillatory Correlates

open access: yesAdvanced Science, EarlyView.
Can a clock change the course of physical fatigue? By covertly manipulating the clock calibration during repeated isometric contractions, we showed that perceived time shapes fatigue accumulation and frontal oscillatory dynamics. While fatigue accumulation was only reduced when the clock was slowed down, frontal oscillatory dynamics followed perceived ...
Pierre‐Marie Matta   +3 more
wiley   +1 more source

Engagement in women's health: a history. [PDF]

open access: yesRes Involv Engagem
Perry AG, Mullins E.
europepmc   +1 more source

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