Results 51 to 60 of about 472,363 (307)
The State of Women's Organizations [PDF]
, 2008 What is the state of women's organizations? Who funds women's rights work? What dynamics are shaping the growth of women's organizations?To answer these questions, AWID surveyed almost 1,000 women's organizations worldwide; reviewed the literature ...
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Why Workers’ Rights Are Not Women’s Rights
Laws, 2015 “Why workers’ rights are not women’s rights” is an argument whose purpose is to make clear why workers’ rights rest on a masculine embodiment of the labor subject and it is this masculine embodiment which is at the center of employment contracts and ...
Heidi Gottfried
doaj +1 more source
Statecraft and Pursuing Women's Rights in Africa [PDF]
, 2016 This particular primer maps key areas of feminist analysis and intervention in governance. Based on existing research on the major factors that hinder women's political participation, emphasis is placed on electoral systems, political parties, quotas and
Awino Okech
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Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
The Millennium Development Goals And Reproductive Health: Moving Beyond the UN [PDF]
, 2005 One of a series of reports for the foundation on women's rights and poverty ...
Barbara Crossette
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FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
The Journey of Women from Victim to Peace-Maker: Women, Insurgency and Northeast India
Space and Culture, India, 2018 The sufferings of women in any insurgency movement have been the focus of many women's rights and human rights groups in present times. Studies have demonstrated that women have to suffer pain as mothers, sisters, daughters, caregivers and victims during
Piyali Dutta
doaj +1 more source