Results 31 to 40 of about 482,265 (269)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Civil Rights News [PDF]

, 2012
Volume 1-2012 of Civil Rights News by the AFL-CIO Department of Civil, Human and Women\u27s Rights. This Issue covers: Civil Rights, Voting Rights, Immigration, LGBT Developments, Women’s Rights, and additional ...
AFL-CIO
core   +1 more source

Violence as an Under-Recognized Barrier to Women’s Realization of Their Right to Adequate Food and Nutrition: Case Studies From Georgia and South Africa [PDF]

, 2015
This article addresses under-acknowledged barriers of structural violence and discrimination that interfere with women’s capacity to realize their human rights generally, and their right to adequate food and nutrition in particular.
Bellows, Anne C., Jenderedjian, Anna, Lemke, S., Scherbaum, Veronika   +3 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The "First daughter" effect: Human rights advocacy and attitudes toward gender equality in Taliban-controlled Afghanistan.

PLoS ONE
International concern for the human rights of Afghan women has spiked since the Taliban consolidated power in Afghanistan in fall 2021. Yet little is known about how to effectively advocate for women's human rights under this new context.
Kristina Becvar, Charli Carpenter, Bernhard Leidner, Kevin L Young   +3 more
doaj   +1 more source

Using Rights to Counter “Gender-Specific” Wrongs [PDF]

, 2009
One popular strategy of opposition to practices of female genital cutting (FCG) is rooted in the global feminist movement. Arguing that women’s rights are human rights, global feminists contend that practices of FGC are a culturally specific ...
Tobin, Theresa
core   +1 more source

Taking up the cudgels against gay rights? Trends and trajectories in African Christian theologies on homosexuality [PDF]

, 2012
Against the background of the HIV epidemic and the intense public controversy on homosexuality in African societies, this article investigates the discourses of academic African Christian theologians on homosexuality. Distinguishing some major strands in
Abogunrin S. O., Adriaan S. van Klinken, Allen J., Althaus-Reid M., Antonio E., Bujo B., Bujo B., Bujo B., Chitando E., Chitando E., Chitando E., Chitando E., Chitando E., Chukwu C. N., Dube M. W., Dube M. W., Dube M. W., Dube M. W., Englund H., Epprecht M., Frederiks M. T., Frederiks M. T., Gifford P., Gunda M. R., Gwamna D. J., Hassett M. K., Hoad N. W., Igboin B. O., Jenkins P., Kahiga J., Kanyoro M. R. A., Magesa L., Magesa L., Magesa L., Maluleke T. S., Maluleke T. S., Maluleke T. S., Martey E., Martey E., Masenya M., Masiiwa Ragies Gunda, Mbiti J. S., Mbiti J. S., Mombo E., Mugambi J. N. K., Mugambi J. N. K., Murray S. O., Mutambara M., Nabushawo J. C., Nicolson R., Njino J., Njoroge N., Nwaigbo F., Oduyoye M. A., Oduyoye M. A., Oduyoye M. A., Phillips O., Phiri I. A., Phiri I. A., Phiri I. A., Phiri I. A., Phiri I. A., Shisanya C. R. A., Tumwesigye J., Tutu D., UNAIDS, van Klinken A. S., Walligo J., Ward K.   +68 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

WOMEN’S POLITICAL RIGHTS IN INTERNATIONAL LAW AND PRACTICE IN VIETNAM

სამართალი და მსოფლიო
As one of the fundamental human rights, political rights guarantee that persons can equally participate in socio-political life or management of the state and society without any unreasonable restriction. Ensuring women’s political rights is an important
Mac Thi Hoai Thuong
doaj   +1 more source

Fact Finding Report of Violation of the Rights of Workers at Washing Unit of Fibre & Fabrics International Pvt. Ltd. (FFI), Peenya Industrial Area, Bangalore [PDF]

, 2006
Fact finding report conducted by GATWU through various social, human rights and women’s rights organizations and social activists on Fibre & Fabrics International (FFI), a private garment manufacturing company in ...
Garment and Textile Workers Union (GATWU)
core   +1 more source