Results 161 to 170 of about 166,258 (261)

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Women's Empowerment in South Asia and Southeast Asia: A Comparative Analysis

open access: yes
This paper uses multivariate regression analysis to explore the time and birth cohort trends of women’s empowerment in eight countries of South Asia and South East Asia.
Chaudhuri, Sanjukta
core  

"Not just supporting but leading": the involvement of the women of the South Wales coalfield in the 1984-85 Miners' Strike

open access: yes, 2012
The 1984-85 miners’ strike dramatically changed the face of the South Wales Valleys. This dissertation will show that the women’s groups that played such a crucial supportive role in it were not the homogenous entity that has often been portrayed.
Davies, Rebecca
core  

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

open access: yesAdvanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang   +16 more
wiley   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang   +19 more
wiley   +1 more source

WOMEN’S LANGUAGE IN BLACK SWAN MOVIE: A SOCIOLINGUISTIC STUDY

open access: yes, 2018
In communication, women and man have particular characteristics in the use of language. Women who have subordinate role want to achieve particular purposes as they have a certain role in society.
Widyawati, Vany Rimbi
core  

Unmasking microaggressions: Experiences of women in clinical and academic psychiatry and the need for systemic reform. [PDF]

open access: yesBMJ Ment Health
Ojeahere MI   +20 more
europepmc   +1 more source

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