Results 111 to 120 of about 9,547,498 (355)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Preimplantation genetic screening reveals a high incidence of aneuploidy and mosaicism in embryos from young women undergoing IVF [PDF]

, 2005
Esther B. Baart, Elena Martini, Irene van den Berg, N.S. Macklon, R-J.H. Galjaard, Bart C.J.M. Fauser, Diane Van Opstal   +6 more
openalex   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Insights into Perimenopause: A Survey of Perceptions, Opinions on Treatment, and Potential Approaches

Women
Perimenopause, the transitional phase leading up to menopause, affects millions of women worldwide, yet it remains poorly understood and under-addressed in healthcare.
Andrea K. Wegrzynowicz, Amanda C. Walls, Myra Godfrey, Amy Beckley   +3 more
doaj   +1 more source

Glucose Intolerance in a Large Cohort of Mediterranean Women With Polycystic Ovary Syndrome [PDF]

, 2004
Alessandra Gambineri, Carla Pelusi, Elisa Manicardi, Valentina Vicennati, M Cacciari, Antonio Maria Morselli‐Labate, Uberto Pagotto, Renato Pasquali   +7 more
openalex   +1 more source

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong, Shasha Yu, Jing Zhang, Yu Zu, Yujing Zhang, Jing Lv, Xuyang Cao, Xuedan Feng   +7 more
wiley   +1 more source

From Going out Half-Done to Fully Protected: Intrinsic and External Motivators in HPV Vaccine Decision-Making Across Cultures

Women
Background: The introduction of the human papilloma virus (HPV) vaccine has allowed for incredible strides in the reduction in HPV-related cancers. Despite widespread availability and a recent age group expansion for the vaccine, uptake remains low ...
Alina Cernasev, Karissa Cliff, Hayleigh Hallam, Emily Nagel, Alex Johnson, Tracy M. Hagemann   +5 more
doaj   +1 more source

(Dis)Embedded Women [PDF]

, 2002
The central question we were asked to address in the Michigan Journal of International Law\u27s Symposium, Dueling Fates, was, Which international legal approach more effectively protects women\u27s rights, the collective or the individual?
Howard-Hassmann, Rhoda E.
core   +2 more sources

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

Stress, Memory, and Hormonal Influence: Considering Ovarian Hormones in Emotional Memory Intrusions

Women
Women’s greater vulnerability to intrusive memories following trauma may be partially explained by the influence of ovarian hormones on memory consolidation processes.
Kelly A. Daly, Alika Tsytsurina, Danielle M. Mitnick, Amy D. Marshall   +3 more
doaj   +1 more source