Results 51 to 60 of about 6,438,923 (362)

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Being a Black Mother Living with HIV Is a “Whole Story”: Implications for Intersectionality Approach

open access: yesWomen, 2022
While African, Caribbean, and Black (ACB) mothers living with HIV in Canada are required to follow public health guidelines by exclusively formula feeding their infants, they also face cultural expectations from peers and family members to breastfeed ...
Josephine B. Etowa   +2 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Serum Creatine Kinase Increases after Acute Strength Training in College Athletes with Menstrual Irregularities

open access: yesWomen, 2021
Chronic menstrual dysfunction and low female sex hormones adversely affect muscular performance in women but studies in college athletes are scarce. A cohort of 18 Japanese, female college athletes at the University of Tsukuba, Japan, were recruited and ...
Akemi Sawai   +4 more
doaj   +1 more source

Zika Virus Infection in Pregnant Women in Rio de Janeiro — Preliminary Report

open access: yesYearbook of Pediatrics, 2016
BackgroundZika virus (ZIKV) has been linked to central nervous system malformations in fetuses. To characterize the spectrum of ZIKV disease in pregnant women and infants, we followed patients in Rio de Janeiro to describe clinical manifestations in ...
A. Act   +20 more
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

An Increase in Prominent Probiotics Represents the Major Change in the Gut Microbiota in Morbidly Obese Female Patients upon Bariatric Surgery

open access: yesWomen
The global increase in obesity carries inherent health implications, with an increased BMI being a known risk factor for diseases such as type 2 diabetes, cardiovascular diseases, or different cancer types.
Ann-Kathrin Kissmann   +9 more
doaj   +1 more source

Changing the PrEP Narrative: A Call to Action to Increase PrEP Uptake among Women

open access: yesWomen, 2021
Although the incidence of new cases of human immunodeficiency virus (HIV) has decreased in the past decade, in 2018 more than 7000 women with HIV were diagnosed in the United States (US).
Alina Cernasev   +3 more
doaj   +1 more source

Women mentoring women [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2023
Carolyn Chang   +3 more
openaire   +3 more sources

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

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