Results 111 to 120 of about 141,758 (237)

Reflecting on the Occupational Safety and Health Landscape in the Philippines: A Data-driven Imperative. [PDF]

Acta Med Philipp
Fadrilan-Camacho VFF.
europepmc   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

Screen-Printable p- and n‑Type Functionalized Graphene Inks for Flexible Textile Thermoelectric Generators. [PDF]

ACS Omega
Newby S, Ahmed MR, Mirihanage W, Fernando A.   +3 more
europepmc   +1 more source

Where Art Thou? Regional Distribution of Culture Workers in Finland [PDF]

This study seeks to shed light on the regional distribution of culture workers in Finland. What factors – if any - make the location decisions of culture workers different from that of others? This study uses a rich micro level data for an application of
Riikka Penttinen
core  

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

Computer Vision Syndrome Before and After the SARS-CoV-2 Pandemic: New-Symptom Onset and Workplace Setup of Visual Display Terminals. [PDF]

J Occup Environ Med
Behrens T, Griemsmann S, Hosbach I, Wechsler K, Weber B, Clarenbach C, Petersen J, Neubauer B, Ellegast R, Casjens S.   +9 more
europepmc   +1 more source

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

Age and gender distortion in online media and large language models. [PDF]

Nature
Guilbeault D, Delecourt S, Desikan BS.
europepmc   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Computer vision syndrome with academic burnout among college students in majors of medical and health-related fields and the moderating effect of gender. [PDF]

Sci Rep
Hu Z, Pei D, Zhang Y, Yang D, Gao X, Tang F, Deng W, Cai Y, Yun Y, Zhao H, Zhou Y.   +10 more
europepmc   +1 more source