Results 141 to 150 of about 141,234 (236)

Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling

Advanced Science, EarlyView.
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng, Peng Yue, Kaiyu Zhou, Guidong Gong, Yue Zhang, Sha Lin, Xu Liu, Yanjiang Zheng, Siyuan Jing, Junling Guo, Yan Qi, Bi‐Sen Ding, Yimin Hua, Yifei Li   +13 more
wiley   +1 more source

Artificial intelligence in the workplace: a living systematic review protocol on worker safety, health, and well-being implications. [PDF]

Syst Rev
Jetha A, Crouch M, Vold K, Peters SE, Vietas J, Sriharan A, Irvin E.   +6 more
europepmc   +1 more source

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

AI and the Future of Work: Assessing Occupational Social Status Perceptions Among University Students. [PDF]

Behav Sci (Basel)
Liu J, Zhuang Y, Yang H, Li S, Qu C.
europepmc   +1 more source

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu, Haojie Chen, Xiang Li, Jingxin Liu, Yiwen Li, Zhenyi Shi, Shenshen Guo, Qingfeng Du, Aiping Lu, Daogang Guan   +9 more
wiley   +1 more source

Organic Representation as a Critical Media Approach to Leadership Studies in Popular Culture. [PDF]

New Dir Stud Leadersh
Sarkissian R.
europepmc   +1 more source

Intrinsic PPG–ECG Coupling for Accurate and Low‐Power Blood Pressure Monitoring

Advanced Science, EarlyView.
A PPG–ECG coupling strategy for continuous blood pressure monitoring that intrinsically synchronizes signals within a single waveform is demonstrated, minimizing synchronization errors and hardware complexity. This approach halves power consumption while maintaining high accuracy, enabling compact, energy‐efficient wearable devices for personalized ...
Sitong Chen, Hua Luo, Zhentao Yao, Zhou Jiang, Xiaodong Wu, Hanmin Liu   +5 more
wiley   +1 more source

Impact of the Play Active policy intervention on early childhood educator's sedentary behaviour-related practices, psychosocial influences and meeting policy recommendations: Results from a pragmatic cluster randomized trial. [PDF]

Pediatr Obes
Christian H, Nathan A, Adams E, Trost SG, Schipperijn J.   +4 more
europepmc   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Major risk factors of obesity in China and recommendations for future prevention and control efforts: a systematic review and meta-analysis. [PDF]

Lancet Reg Health West Pac
Hu J, Xie J, Liu B, Peng W, Liu B, Yan Y, Zhang L, Wang X, Xi Y, Ma Y, Lu Y, Jiang Y, Chen F, Aris IM, Zhang J, Wen D, Wang Y.   +16 more
europepmc   +1 more source