Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang +11 more
wiley +1 more source
Study on Drying Characteristics of Juvenile Wood of <i>Dalbergia odorifera</i> T.C.Chen. [PDF]
Liu J, Li T, Li J, Liu H.
europepmc +1 more source
Trophic Diversity in Duckweed: Mixotrophy, More Than the Sum of its Extremes
In the context of rising DOC in aquatic environments, mixotrophic duckweed may impact carbon cycling by acting as either a carbon sink, as they absorb CO2 through photosynthesis, or a carbon source, as they release CO2 through respiration of absorbed DOC, which depends on DOC concentration, light availability, temperature, and other environmental ...
Zuoliang Sun +5 more
wiley +1 more source
Processing and End-Uses of Wood Affected by Forest Fires, Eastern Spruce Budworm and Mountain Pine Beetle Outbreaks. [PDF]
Garcia R +3 more
europepmc +1 more source
Primary Driving Force in Wood Vacuum Drying
The objective of this research based on both the theory and experimentation was to prove that the total pressure difference is the primary driving force during the vacuum drying.
Chen, Zhangjing
core
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen +11 more
wiley +1 more source
Compound-Resolved VOC Dynamics in a Full-Scale Medium-Density Fibreboard Dryer: Process-State Screening Across Wood Furnish, Amino Resin Dosing, and Thermal Operating Variables. [PDF]
Nedić V, Paul A, Barbu MC, Kristak L.
europepmc +1 more source
NLSS3 Impairs SHM1 Autophagic Degradation to Regulate Leaf Morphology and Salt Tolerance in Rice
In rice, NLSS3 binds and shields SHM1 from autophagic degradation to maintain serine homeostasis. The A132P mutation in nlss3 disrupts this, triggering SHM1 loss, metabolic dysfunction, K+ imbalance, and impaired ROS scavenging, which collectively drive narrow leaves and salt sensitivity.
Xiong Liu +15 more
wiley +1 more source
Selective cellulose fibril release from hardwoods libriform tissue. [PDF]
von Usslar F +2 more
europepmc +1 more source
A layered bead‐network wallpaper is designed to modulate the light propagation path, overcoming the color residue limitations of thermochromic components for efficient automatic switching between radiative cooling and solar heating modes. The layered bead‐network wallpaper provides passive, all‐season thermal regulation while offering self‐cleaning and
Jianyu Wu +7 more
wiley +1 more source

