Results 61 to 70 of about 126,068 (298)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Screening of potential chemical marker with interspecific differences in Pterocarpus wood and a spatially-resolved approach to visualize the distribution of the characteristic markers

Frontiers in Plant Science, 2023
Profiling the spatial distributions and tissue changes of characteristic compounds with interspecific differences is critical to elucidate the complex species identification during tree species traceability, wood anti-counterfeiting verification and ...
Bo Liu, Qian Chen, Lina Tang, Liming Zhu, Xianwu Zou, Botao Li, Wei Fan, Yuejin Fu, Yun Lu   +8 more
doaj   +1 more source

Ebony Wood Identification to Battle Illegal Trade [PDF]

Biodiversity Information Science and Standards, 2019
Illegal logging is a serious global issue. It is not only a great threat to rare forest species, but also contributes to the current biodiversity crisis and climate change. Despite international agreements, 10-30% of all imported wood has been illegally logged.
Jahanbanifard, M., Gravendeel, B., Lens, F.P., Verbeek, F.J.   +3 more
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Timber Structures of Florence Cathedral: Wood Species Identification, Technological Implications and Their Forest Origin

, 2023
The Cathedral of Florence is one of the largest churches in the world and is known for one of the most famous domes ever, which characterizes the skyline of the city.
Ilaria Stefani, Marco Degl’Innocenti, Nicola Macchioni, Simona Lazzeri, Samuele Caciagli, Francesca Mannucci   +5 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Identification of Wood Treated with Waterborne Metal-Based Preservatives

, 2006
Preservative chemicals are added to wood products to prevent biological deterioration of the wood from insects and fungi. In warm humid climates, wood exposed to the outdoor environment will last only 1 to 2 years, whereas the structural integrity of the

core   +1 more source

Stakeholder perceptions of wood-based products in the built environment : a literature review

, 2023
Current global environmental challenges, such as climate change, set an urge to seek renewable low-emission alternatives to substitute fossil fuel-derived products while transitioning towards circular bioeconomy.
Kunttu, Janni, Leskinen, Pekka, Wallius, Venla, Van Brusselen, Jo, Näyhä, Annukka   +4 more
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Antagonistic Properties and Screening of Bacillus Velezensis Nhw-B72 against Wood Fungal Decay

, 2021
(1) Background: Wood decay is a serious issue that results from the presence of wood-destroying fungi and has a great influence on the international wood industry. The utilization of biological control methods offers good prospects for wood preservation.
Ping Zhang, Yan Zhong, Guoqi Xu, Lihai Wang, Congxun Huang, Pengwei Zhao   +5 more
core   +1 more source