Results 171 to 180 of about 24,263 (254)

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

Advanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong, Wenlong Chen, Fanglong Liu, Shengyi Zhou, Bolin Yu, Yuying Wang, Xiqian Zhou, Xuehui Wang, Diya Liu, Zhuoyu Zhang, Xinran Wang, Mounia Lalouly, Yiwen Li, Zhefei Du, Tao Yan, Zhihui Xiao, Zhou Zhou, Huanhuan Zhu, Fengyuan Qian, Bowen Zheng, Lin Fang   +20 more
wiley   +1 more source

Cognitive and functional status after transcatheter and mini-aortic valve replacement: a prospective cohort study. [PDF]

J Cardiothorac Surg
Dewan KC, Sabatino ME, Cuccurullo SJ, Joki JB, Fleming TK, Boylston M, Macor M, Coyle S, Wang SY, Chao J, Lee LY.   +10 more
europepmc   +1 more source

Bioinspired Multifunctional Flexible C‐SiC Fibrous Aerogel for Superior Electromagnetic Interference Shielding Under Extreme Environments

Advanced Science, EarlyView.
This schematic presents a biomimetic C‐SiC fibrous aerogel inspired by the special structure of momordica charantia. It exhibits outstanding thermal insulation and ultrahigh specific electromagnetic shielding performance, together with excellent high‐temperature stability and mechanical flexibility, showing great promise for aerospace applications ...
Tianyue Yang, Yan Shen, Zhongqian Zhao, Xue Zhou, Qianji Chen, Xujing Wang, Chuchu Zheng, Zhaoxiang Lu, Yangzhong Zhao, Yanzi Gou   +9 more
wiley   +1 more source

Research on the development of Chaozhou woodcarving from the perspectives of grounded theory and biomechanics. [PDF]

PLoS One
Li L, Wu F, Zang W, Fan L.
europepmc   +1 more source

Bioinspired Passive Flow Routing to Mitigate Thrombosis in Prosthetic Heart Valves and Cardiovascular Devices

Advanced Science, EarlyView.
Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin, Mark Epshtein, Yahel Talmon, Tirosh Mekler, Itay Or, Mahli Raad, Gil Bolotin, Josué Sznitman, Netanel Korin   +8 more
wiley   +1 more source

Evaluating the Molecular Potential and Interpretability of DNA in Historical Spirit Collection Media. [PDF]

Mol Ecol Resour
Tulloch RL, Rojahn J, Neaves LE, Trujillo-González A, Holleley CE, Hahn EE.   +5 more
europepmc   +1 more source

Deep Learning Network‐Tailored Microenvironment Matching of 4D Bioprinting Bioactive Scaffolds for Bone Regeneration

Advanced Science, EarlyView.
A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang, Yuechi Zhang, Weifeng Hu, Shiyan Lv, Fan Jia, Yan Zhang, Feng Wu, Changjiang Yang, Guanqi Zhen, Jinglong Yan, Xu Cui, Wei Zhao, Guanghua Chen   +12 more
wiley   +1 more source

Performance of Polystyrene-Impregnated and CCA-Preserved Tropical Woods Against Subterranean Termites in PNG Field and Treatment-Induced Color Change. [PDF]

Polymers (Basel)
Hadi YS, Yosi C, Marai P, Mubarok M, Abdillah IB, Pari R, Pari G, Syukur A, Zaini LH, Hermawan D, Liao J.   +10 more
europepmc   +1 more source

Longitudinal Single‐Axon‐Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant

Advanced Science, EarlyView.
A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky, Emma Anisman, Ron Perez, Sophia Zhang, Morgan Hoffman, Daniel Hunter, Abigail Cherian, Jevon Bonner, Emilia Feria, Ahmed Ahmed, Muneeb Malik, Junwei Du, Leland C. Sudlow, David M. Brogan, Matthew D. Wood, Mikhail Y. Berezin   +15 more
wiley   +1 more source

Multi-Analytical Assessment of Deterioration in the Qianlong Tripitaka Wooden Scripture Plates. [PDF]

Polymers (Basel)
Wu W, Peng Y, Zha J, Zhang G, Lv M, Wang Y.   +5 more
europepmc   +1 more source