Results 21 to 30 of about 1,486,393 (207)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

PEN GAWETAN KAYU MANGIUM SECARA RENDAMAN PANAS-DINGIN DENGAN BAHAN PENGAWET BORON DAN CCB

open access: yesJurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2017
Wood materials from plantation timber, among others is mangium (Acacia mangium Willd.) are supposed to be more susceptible to the wood-degrading organisms.
Djarwanto Djarwanto, R Sudradjat
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Density distribution in middle-sized silver birch wood (Betula pendula Roth)

open access: yesDrewno
The paper contains a comprehensive analysis of the variability of density in middle-sized specimens of silver birch (Betula pendula Roth). Wood density tests were carried out using transverse and longitudinal sections of five middle-sized silver birch ...
Ewa Dobrowolska, Sławomir Krzosek
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Resistance of TiO2-treated Eucalyptus botryoides Wood to the Fungus Ganoderma applanatum

open access: yesFloresta e Ambiente, 2018
The aim of the present study is to investigate the resistance of Eucalyptus botryoides treated with TiO2 particles to attack by the fungus Ganoderma applanatum.
Paula Zanatta   +6 more
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

open access: yesMolecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani   +7 more
wiley   +1 more source

Effect of nano zinc oxide on physical and mechanical properties of wood plastic composites [PDF]

open access: yesIranian Journal of Wood and Paper Industries, 2017
In this study, the effects of nano zinc oxide on the physical and mechanical properties of wood-polyethylene composites were investigated. The composites containing 0, 1, 2 and 4 wt% zinc oxide nanoparticles were manufactured using an internal mixer and ...
Davood Rasouli   +2 more
doaj  

The bio-mechanical properties of coco wood applied with Neem extracts: a potential preservative for sustainable building in Marinduque, Philippines

open access: yesSustainable Environment Research, 2019
The purpose of this study was to develop an organic wood preservative from the liquid extract of Neem tree (Azadirachta indica). This product has the potential in controlling the fast deterioration of coco wood by extracting liquid from fruits with seeds
Froilan P. Ney   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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