Results 61 to 70 of about 153,833 (307)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Sight versus Sound: Do Visual Assessments of Dead Standing Trees Reflect Acoustic Nondestructive Evaluations of Wood Quality? [PDF]

, 2022
The forest industry typically uses visual appearance to evaluate the wood quality when salvaging dead standing trees. We investigated whether the visual appearance of white spruce (Picea glauca (Moench) Voss) defoliated by the spruce budworm ...
Hovde, Tyler J., Forsman, John W., Xie, Xinfeng, Xiping Wang, Wang, Xiping, Tyler Hovde, Xinfeng Xie, Ross, Robert J., Rudnicki, Mark, Mark Rudnick, Dickson, Yvette L., John Forsman, Yvette Dickson, Robert Ross   +13 more
core   +2 more sources

Wood Properties and Quality

Abstract Trees in continuous cover forestry (CCF) typically form very narrow rings at young ages in suppressed positions but can grow very quickly at older ages in dominant positions, maintaining long-lived crowns. CCF trees have slightly higher mean wood density in stems than
Piispanen, Riikka, Pyörälä, Jiri, Valkonen, Sauli   +2 more
openaire   +2 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Interfamily variation in wood quality of black spruce in a northwestern Ontario progeny trial [PDF]

, 2020
The right trees for replanting must be selected to ensure optimal future forest conditions. Based on desired future outcomes, various progenies can be selected to suit these needs.
Balogh, Istvan
core  

Frost Crack Impact on European Beech (Fagus sylvatica L.) Wood Quality [PDF]

, 2015
Frost crack represents one of the main defects which affect European beech wood quality. Therefore, the purpose of this paper is to improve the knowledge regarding both the impact of frost crack on European beech wood quality and the frost crack ...
CÂMPU, Vasile R., Vasile R. Câmpu, DUMITRACHE, Radu, Radu Dumitrache   +3 more
core   +2 more sources

Variação axial e efeito do desbaste na massa específica das árvores centrais de Eucalyptus grandis Axial variation and effect of thinning on basic density of central trees of Eucalyptus grandis

Ciência Rural, 2012
Este estudo teve como objetivo avaliar a variação axial e o efeito do desbaste na massa específica das árvores centrais de Eucalyptus grandis aos 18 anos de idade.
Rômulo Trevisan, Elder Eloy, Luciano Denardi, Clovis Roberto Haselein, Braulio Otomar Caron   +4 more
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A review of the effects of silviculture on wood quality [PDF]

, 2010
This paper reviews the effects of silviculture on wood quality. The term silviculture is employed to encompass a broad range of forest management practices which may alter a forest’s composition, growth, and environment.
Hart, James Foster
core