Results 91 to 100 of about 20,071,388 (255)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Information system quality in work-life balance
Knowledge Management & E-Learning: An International Journal, 2016 This paper aims to look for the role information systems quality may play in work-life balance among Malaysian ICT employees. The results of this study will be useful in the development of new tools and technologies that are focused on ISQ dimensions ...
Sharmini Gopinathan, Murali Raman
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Work-life balance in Spanish Firms: Still on the to-do list [PDF]
The purpose of this paper is to analyse the perception of institutional pressures on employers to improve work-life balance, and to classify organizations according to those perceptions.
Ramón Valle, Susana Pasamar
core
Work-life balance and psychological and stress-related issues in digital workspaces
, 2023 reservedThe emergence of digital technology has provided greater flexibility and autonomy in the workplace, allowing employees to work from anywhere and at any time.
PJEVIC, DOROTEJA
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tipping the balance: the problematic nature of work–life balance in a low-income neighbourhood. [PDF]
The article attempts to locate the contested notion of work–life balance within the context of global trends and recent policy developments. It describes a small-scale qualitative study of work–life balance as it is experienced within a low-income ...
Dean, Hartley
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Improving work and life balance : building a multilevel model of work-life balance focusing on group structure and relational job design [PDF]
, 2013 One in five Australian workers believes that work doesn’t fit well with their family and social commitments. Concurrently, organisations are recognising that to stay competitive they need policies and practices that support the multiple aspects of ...
Chang, Artemis, Bradley, Lisa M.
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The Influence of Work-Life Balance Benefits on Family-Supportive Organisational Perception and Work Attitudes [PDF]
, 2010 This study investigated the relationship between the availability of, and the use of, work-family balance policies offered by organisations and family-supportive organisational perception (FSOP), work-to-family conflict, continuance and affective ...
Herlin, Paula Kristina
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