Results 181 to 190 of about 1,338,925 (305)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

COVID-19 ON EMPLOYEES UNDERSTANDING WORK-LIFE CONFLICT TO WORK-LIFE COUNTERBALANCE

open access: yes
ABSTRACTThe objective of this research is to study the work-family conflict of employees in the insurance sector. Theresearch was conducted among employees in the insurance sector concerning work-family conflict entailsattaining equilibrium between professional work and other activities so that it reduces friction between workfamily conflicts.
openaire   +2 more sources

Managing Organizational Conflict [PDF]

open access: yes
The concept of conflict, being an outcome of behaviours, is an integral part of human life. Wherever there is a difference of opinion there are chances of conflict. Managing conflict effectively demands multifarious professional abilities and acumen.
Mitali PATHAK
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Work-life conflict and its health effects on Moroccan gastroenterologists: a cross-sectional study. [PDF]

open access: yesTher Adv Gastroenterol
Aourarh B   +5 more
europepmc   +1 more source

Work-family conflict: a survey of Singaporean workers

open access: yes, 2003
Work and family are the two most important aspects of people’s lives and they often conflict. This paper examines the nature of that conflict and its effects on managers.
Skitmore, Martin, Ahmad, Sariati
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

War and Women’s Work: Evidence from the Conflict in Nepal [PDF]

open access: yes
In a study of the effect of war on women’s work, this paper examines how Nepal’s 1996-2006 civil conflict affected women’s decisions to engage in employment.
Yana van der Meulen Rodgers   +1 more
core  

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