Improving the mental health of working women with work-life conflict: A protocol development for an explanatory mixed method study. [PDF]
J Educ Health Promot, 2023 Hosseini Z +5 more
europepmc +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Employee posts on personal social media: the mediation role of work-life conflict on employee engagement. [PDF]
Curr Psychol, 2023 Zhou Q, Li H, Li B.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Parenting without Predictability: Precarious Schedules, Parental Strain, and Work-Life Conflict. [PDF]
RSF, 2022 Luhr S, Schneider D, Harknett K.
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Onset of Work-Life Conflict Increases Risk of Subsequent Psychological Distress in the Norwegian Working Population. [PDF]
Int J Environ Res Public Health, 2022 Marti AR, Degerud E, Sterud T.
europepmc +1 more source
Teachersrsquo; perception of work-life conflict
, 2018 In the last decades, the issue of work-life balance has become very important because of the intensification of work, the high performance demands and the structural changes that took place in the contemporary society. The paper explores the work-related and familyrelated sources of work-life conflicts of the pre-university educators from Galati County.
David, S., Lukacs, E.
openaire +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Job autonomy and work-life conflict: A conceptual analysis of teachers' wellbeing during COVID-19 pandemic. [PDF]
Front Psychol, 2022 Khawand S, Zargar P.
europepmc +1 more source